Carbohydrate Esterase Family 5

Known Activities	acetyl xylan esterase (EC 3.1.1.72); cutinase (EC 3.1.1.74)
3D Structure Status	(a/b/a)-sandwich
Note	There are many cutinases in the databanks. Only an example is given here as cutinases act on cutin rather than on carbohydrate esters.
External resources	HOMSTRAD; InterPro; PFAM; PROSITE;
Commercial Enzyme Provider(s)	PROZOMIX;
Statistics	GenBank accession (476); Uniprot accession (180); PDB accession (18); 3D entries (6); cryst (0)

Summary

All (415) Bacteria (301) Eukaryota (113) unclassified (1) Structure (6 ) Characterized (17)

Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
cutinase (CutAB1;AB01674_1)	3.1.1.74		AAA03470.1
cutinase (AN7541.2)	3.1.1.74	Aspergillus nidulans FGSC A4	ABF50887.1 EAA62121.1
cutinase (AN7180.2)	3.1.1.74	Aspergillus nidulans FGSC A4	ABF50882.1 EAA61432.1	C8VD42
triacylglycerol lipase (TglA)	3.1.1.3	Aspergillus oryzae RIB128	BAA92327.1	Q9P960
cutinase (AO090005000029)	3.1.1.74	Aspergillus oryzae RIB40	BAE55151.1		3GBS[A] 3QPD[A]
triacylglycerol lipase (TglA;AO090003001507)	3.1.1.3	Aspergillus oryzae RIB40	BAE58548.1
acetylxylan esterase (Axe2)	3.1.1.72	Chrysosporium lucknowense C1	ADZ98863.1
cutinase (Cle;Cle1)	3.1.1.74	Cryptococcus sp. S-2	BAC67242.1 BAK82405.1	Q874E9	2CZQ[A,B]
cutinase 1 (CutA;Cut1)	3.1.1.74	Fusarium solani pisi	AAA33334.1 AAA33335.1	P00590.1	1CUS[A] 2CUT[A] 3EF3[A] 3ESA[A,B] 3ESB[A] 3ESC[A] 3ESD[A] 3QPC[A]
cutinase	3.1.1.74	Glomerella cingulata	AAL38030.1	P11373	3DCN[A] 3DD5[A,B,C,D,E,F,G,H] 3DEA[A,B]
cutinase	3.1.1.74	Humicola insolens	AAE13316.1 AAE13317.1 ABC06408.1
acetylxylan esterase (Axe1;AcXEI)	3.1.1.72	Hypocrea jecorina RUTC-30	CAA93247.1	Q99034	1QOZ[A,B]
cutinase (Cut1;ThCut1)	3.1.1.74	Hypocrea lixii CECT 2413 / T34	ABN48556.1 AFD53805.1	A8QPD8
cutinase (Cut1)	3.1.1.74	Monilinia fructicola	AAM10822.1 AAZ95012.1	Q2VF46 Q8TGB8
acetylxylan esterase	3.1.1.72	Penicillium aurantiogriseum	CAZ65690.1
acetyl xylan esterase II (Axe2;Axe-2;AxeII;AcXEII)	3.1.1.72	Penicillium purpurogenum MYA-38	AAC39371.1	O59893.1	1BS9[A] 1G66[A] 2AXE[A]
cutinase (Pbc1)	3.1.1.74	Pyrenopeziza brassicae JH26	CAB40372.1	Q9Y7G8

Footnotes

Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.