Carbohydrate Esterase Family 14

Activities in FamilyDiacetylchitobiose deacetylase (EC 3.5.1.-);
Chitin disaccharide deacetylase (RE) (EC 3.5.1.105);
Mycothiol S-conjugate amidase (EC 3.5.1.115);
Chitin disaccharide deacetylase (NRE) (EC 3.5.1.136);
N-acetylglucosamine deacetylase (EC 3.5.1.33);
N-acetylglucosaminylphosphatidylinositol deacetylase (EC 3.5.1.89);
Mechanism
3D Structure Statusa/β-fold
Statistics GenBank accession (9701); Uniprot accession (10); PDB accession (18); 3D entries (6); cryst (0)
Archaea
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 N,N'-diacetylchitobiose deacetylase (Pf-Dac; PF0354) 3.5.1.105 Pyrococcus furiosus DSM 3638 AAL80478.1
NP_578083.1
Q8U3V1
3WL4[A,B] 1.54
4XLZ[A,B,C,D,E,F] 1.51
4XM0[A,B,C,D,E,F] 2.80
4XM1[A,B,C,D,E,F] 1.80
4XM2[A,B,C,D,E,F] 2.30
 N,N'-diacetylchitobiose deacetylase / N-acetylglucosamine deacetylase (DacPh; Ph-Dac; PH0499) 3.5.1.33
3.5.1.136
Pyrococcus horikoshii OT3 BAA29587.1 O58235
3WE7[A,B,C] 1.55
3WL3[A,B,C] 2.00
5B2E[A,B,C] β-D-GlcpN
1.80
5B2F[A,B,C] β-D-GlcpN
1.90
 diacetylchitobiose deacetylase (Pch-Dac; CHITON_0574) 3.5.1.136 Thermococcus chitonophagus DSM 10152 CUX77353.1 A0A160VQZ8
8BGN[A,B,C] 2.76
8BGO[A,B,C,D,E,F,G,H,I,J, β-D-GlcpNAc-(1-4)-β-D-GlcpNAc
3.08
8BGP[A,B,C,D,E,F] 2.51
Bacteria
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 diacetylchitobiose deacetylase (BshB; BcZBP; BC1534) 3.5.1.- Bacillus cereus ATCC 14579 AAP08514.1 Q81FP2
2IXD[A,B] 1.8
 BSU22470 (BshB; YpjG)   Bacillus subtilis subsp. subtilis str. 168 CAB14163.2
AIY93569.1
AQR82257.1
AQR86471.1
 
6P2T[A] 1.85
6ULL[A] <non_carb>-(1-2)-α-D-GlcpN-(1-1)-<non_carb>
1.45
 N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-α-D-glucopyranoside deacetylase (MshB; Rv1170) 3.5.1.89 Mycobacterium tuberculosis H37Rv CAA15847.1
AFN49074.1
CCP43926.1
NP_215686.1
P9WJN3
1Q74[A] 1.70
1Q7T[A] β-D-Glcp-(1-1)-methyl
β-D-Glcp-(1-1)-octyl
1.90
4EWL[A,B] 1.85
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