Carbohydrate Esterase Family 10

Known Activities	arylesterase (EC 3.1.1.-); carboxyl esterase (EC 3.1.1.3); acetylcholinesterase (EC 3.1.1.7); cholinesterase (EC 3.1.1.8); sterol esterase (EC 3.1.1.13); brefeldin A esterase (EC 3.1.1.-).
3D Structure Status	(a/b/a)-sandwich
Note	WARNING: because the vast majority (if not all) of the members of this family are esterases acting on non-carbohydrate substrates, the information on this page is no longer updated (August 2002).
External resources	Cholinesterases Page;
Statistics	GenBank accession (867); Uniprot accession (380); PDB accession (56); 3D entries (10); cryst (0)

All (407) Archaea (26) Bacteria (159) Eukaryota (222) Structure (10 ) Characterized (53)

Archaea
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
APE_1547.1 (APE1547)		Aeropyrum pernix K1	BAA80546.1 NP_148014.1	Q9YBQ2	1VE6[A,B]
carboxylesterase (AF1716)		Archaeoglobus fulgidus DSM 4304	AAB89533.1 NP_070544.1	O28558	1JJI[A]
Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
carboxylesterase (Est2)	3.1.1.-	Alicyclobacillus acidocaldarius			1QZ3[A] 1EVQ[A]
brefeldin A esterase	3.1.1.-	Bacillus subtilis	AAC12774.1	O68884	1JKM[A,B]
p-nitrobenzyl esterase	3.1.1.-	Bacillus subtilis NRRL B8079	AAA81915.1	P37967	1C00[A] 1QE3[A] 1QE8[A]
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
cholesterol esterase	3.1.1.13 3.1.1.3	Bos taurus	AAA56788.1	P30122.2	1AKN[A] 1AQL[A,B] 2BCE[A]
acetylcholinesterase	3.1.1.7	Homo sapiens	AAA68151.1 AAP22365.1 NP_000656.1	P22303.1	1B41[A] 1F8U[A]
lipase	3.1.1.-	Homo sapiens	AAA51973.1 AAA52014.1 AAC26514.1 CAA38325.1 CAC27310.1 NP_001798.1 XP_035051.1 XP_035052.1 XP_035053.1 XP_035054.1	Q9UP41	1F6W[A]
liver carboxylesterase	3.1.1.1	Oryctolagus cuniculus	AAC39258.1	P12337	1K4Y[A]
acetylcholinesterase	3.1.1.7	Torpedo californica	CAA27169.1 CAB37951.1	P04058.2 Q9W6Y8	1ACJ[A] 1ACK[nd] 1ACL[A] 1AMN[A] 1AX9[A] 1CFJ[A] 1DX6[A] 1E3Q[A] 1E66[A] 1EA5[A] 1EEA[A] 1EVE[A] 1FSS[A] 1GPK[A] 1GPN[A] 1GQR[A] 1GQS[A] 1H22[A] 1H23[A] 1HBJ[A] 1JJB[A] 1OCE[A] 1QID[A] 1QIE[A] 1QIF[A] 1QIG[A] 1QIH[A] 1QII[A] 1QIJ[A] 1QIK[A] 1QIM[A] 1QTI[A] 1SOM[A] 1VOT[A] 1VXO[A] 1VXR[A] 2ACE[A] 2ACK[A] 2DFP[A] 3ACE[nd] 4ACE[nd]