Carbohydrate Esterase Family 10

Known Activities	arylesterase (EC 3.1.1.-); carboxyl esterase (EC 3.1.1.3); acetylcholinesterase (EC 3.1.1.7); cholinesterase (EC 3.1.1.8); sterol esterase (EC 3.1.1.13); brefeldin A esterase (EC 3.1.1.-).
3D Structure Status	(a/b/a)-sandwich
Note	WARNING: because the vast majority (if not all) of the members of this family are esterases acting on non-carbohydrate substrates, the information on this page is no longer updated (August 2002).
External resources	Cholinesterases Page;
Statistics	GenBank accession (876); Uniprot accession (397); PDB accession (56); 3D entries (10); cryst (0)

Summary

All (407) Archaea (26) Bacteria (159) Eukaryota (222) Structure (10 ) Characterized (53)


Archaea
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
acylaminoacyl-peptidase (PAB1300)	3.4.19.1	Pyrococcus abyssi GE5	CAB50502.1 NP_127272.1	Q9UYB0
Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
arylesterase (Est1)	3.1.1.-	Acetobacter pasteurianus	BAA25191.1	O66374
benzyl esterase (AreA)	3.1.1.-	Acinetobacter sp. ADP1	AAD34027.1	Q9XC26
acetyl-hydrolase (ChnC)	3.1.1.-	Acinetobacter sp. SE19	AAG10029.1	Q9F7D7
carboxylesterase (Est2)	3.1.1.-	Alicyclobacillus acidocaldarius			1QZ3[A] 1EVQ[A]
carboxylesterase	3.1.1.1	Bacillus licheniformis DSM 12369	CAC51386.1	Q93LA4
carboxyl esterase A (EstA)	3.1.1.-	Bacillus pumilus	AAG09918.1	Q9F6C1
type B carboxylesterase (EstA1)	3.1.1.1	Bacillus sp. BP-7	CAB93516.1	Q9L378
brefeldin A esterase	3.1.1.-	Bacillus subtilis	AAC12774.1	O68884	1JKM[A,B]
p-nitrobenzyl esterase	3.1.1.-	Bacillus subtilis NRRL B8079	AAA81915.1	P37967	1C00[A] 1QE3[A] 1QE8[A]
xylanase B (XynB)	3.2.1.8	Butyrivibrio fibrisolvens H17C	CAA43712.1	P26223
polyurethane esterase (PudA;CBS;PUR)	3.1.1.-	Delftia acidovorans TB-35	BAA76305.1	Q9WX47
pectin acetylesterase (PaeX;Dda3937_03363)	3.1.1.-	Dickeya dadantii 3937	ADM98623.1 CAD45188.1	Q83V97
acetyl esterase (YbaC)	3.1.1.-	Escherichia coli K-12 MG1655	AAB40230.1 AAC73578.1 NP_415009.1	P23872
carboxylesterase (EstA)	3.1.1.3	Paenibacillus barcinonensis BP-23	CAB42083.1	Q9X6Z3
lipase	3.1.1.3	Psychrobacter sp. St1	AAF70342.1	Q9L514
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
acetylcholinesterase	3.1.1.7	Apis mellifera	AAG43568.1	Q9GQP7
cholesterol esterase	3.1.1.13 3.1.1.3	Bos taurus	AAA56788.1	P30122	1AKN[A] 1AQL[A,B] 2BCE[A]
acetylcholinesterase (Ace-4)	3.1.1.7	Caenorhabditis briggsae	AAF80378.1	Q9NDG8
acetylcholinesterase C (Ace-3)	3.1.1.7	Caenorhabditis briggsae	AAF80377.1	Q9NDG9
carboxylesterase b1 (Estbeta1)	3.1.1.-	Culex tritaeniorhynchus	AAG09281.1	Q9GU95
acetylcholinesterase	3.1.1.7	Danio rerio	AAI63891.1 AAI63898.1 CAC19790.1 NP_571921.1	B3DKL4 Q9DDE3
acetylcholinesterase	3.1.1.7	Dictyocaulus viviparus	AAG34705.1	Q9GPL0
carboxyl esterase (Est6)	3.1.1.1	Drosophila erecta	CAC43297.1	Q95ZG1
carboxyl esterase (Est6)	3.1.1.1	Drosophila yakuba	CAC43299.1	Q95ZE5
butyrylcholinesterase (BCHE)	3.1.1.8	Equus caballus	AAF61480.1	Q9N1N9
acetylcholinesterase	3.1.1.7	Felis catus	AAC08995.1	O62763
butyrylcholinesterase	3.1.1.8	Gallus gallus	CAC37792.1	Q90ZK8
carboxyl-ester lipase	3.1.1.-	Gorilla gorilla	AAF71700.1	Q9N1D1
acetylcholinesterase	3.1.1.7	Homo sapiens	AAA68151.1 AAP22365.1 NP_000656.1	P22303	1B41[A] 1F8U[A]
butyrylcholinesterase	3.1.1.8	Homo sapiens	AAA52015.1 AAA98113.1 AAA99296.1 AAH18141.1 NP_000046.1 XP_049839.1 XP_049840.1 XP_049841.1	P06276
carboxylesterase 3 (Brain) (CES3)	3.1.1.-	Homo sapiens	NP_036254.1
lipase	3.1.1.-	Homo sapiens	AAA51973.1 AAA52014.1 AAC26514.1 CAA38325.1 CAC27310.1 NP_001798.1 XP_035051.1 XP_035052.1 XP_035053.1 XP_035054.1	Q9UP41	1F6W[A]
juvenile hormone esterase	3.1.1.-	Manduca sexta	AAG42021.1	Q9GPG0
acetylcholinesterase	3.1.1.7	Meloidogyne incognita	AAD02835.1	O96529
acetylcholinesterase	3.1.1.7	Meloidogyne javanica	AAD25921.1	Q9XYA9
butyrylcholinesterase (Bche)	3.1.1.8	Mus musculus	NP_033868.1	Q03311 Q499C7 Q543J3
carboxylesterase 1 (Ces1)	3.1.1.1	Mus musculus	AAH21150.1 AAH26897.1 NP_067431.2	Q3UW56 Q8VCC2
arylacetamide deacetylase	3.1.1.-	Mus musculus	AAG60035.1 BAB25554.1 NP_075872.1	Q99PG0
acetylcholinesterase	3.1.1.7	Mus musculus	AAK28044.1
carboxylesterase ML1 (CESmML1)	3.1.1.1	Mus musculus	BAB60699.1	Q924V7
carboxylesterase MH1 (CESmMH1)	3.1.1.1	Mus musculus	BAB60698.1	Q8VCT4
acetylcholinesterase	3.1.1.7	Musca domestica COOPER	CAC39209.1	Q95P20
acetylcholinesterase	3.1.1.7	Nephotettix cincticeps HIRATSUKA	AAF65202.1	Q9NJH6
acetylcholinesterase A	3.1.1.7	Nippostrongylus brasiliensis	AAK44221.1	Q967G8
liver carboxylesterase	3.1.1.1	Oryctolagus cuniculus	AAC39258.1	P12337	1K4Y[A]
carboxylic ester hydrolase	3.1.1.1	Rattus norvegicus	AAL00849.1	P16303 Q91YG2
butyrylcholinesterase (Bche)	3.1.1.8	Rattus norvegicus	AAF44713.1 NP_075231.1	Q9JKC1
cholesterol esterase (Cel)	3.1.1.-	Rattus norvegicus	NP_058693.1	G3V7G2 P07882
arylacetamide deacetylase	3.1.1.-	Rattus norvegicus	AAD56394.1 AAF74757.1 NP_065413.1	Q9QZH8
acetylcholinesterase 2	3.1.1.7	Rhipicephalus microplus ULTIMO	CAB93508.1 CAB93509.1 CAB93510.1 CAB93511.1	Q9NFK1 Q9NFK2 Q9NFK3 Q9NFK4
acetylcholinesterase	3.1.1.7	Schizaphis graminum	AAK09373.1	Q9BMJ1
acetylcholinesterase	3.1.1.7	Torpedo californica	CAA27169.1 CAB37951.1	P04058 Q9W6Y8	1ACJ[A] 1ACK[nd] 1ACL[A] 1AMN[A] 1AX9[A] 1CFJ[A] 1DX6[A] 1E3Q[A] 1E66[A] 1EA5[A] 1EEA[A] 1EVE[A] 1FSS[A] 1GPK[A] 1GPN[A] 1GQR[A] 1GQS[A] 1H22[A] 1H23[A] 1HBJ[A] 1JJB[A] 1OCE[A] 1QID[A] 1QIE[A] 1QIF[A] 1QIG[A] 1QIH[A] 1QII[A] 1QIJ[A] 1QIK[A] 1QIM[A] 1QTI[A] 1SOM[A] 1VOT[A] 1VXO[A] 1VXR[A] 2ACE[A] 2ACK[A] 2DFP[A] 3ACE[nd] 4ACE[nd]
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Footnotes

Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.