Carbohydrate-Binding Module Family 50

Activities in FamilyModules of approx. 50 residues found attached to various enzymes from families GH18, GH19, GH23, GH24, GH25 and GH73, i.e. enzymes cleaving either chitin or peptidoglycan. Binding to chitopentaose demonstrated in the case of Pteris ryukyuensis chitinase A [Ohnuma T et al. (2008) J. Biol. Chem. 283:5178-87 (PMID: 18083709)]. CBM50 modules are also found in a multitude of other enzymes targeting the petidoglycan such as peptidases and amidases. These enzymes are not reported in the list below.
NoteAlso known as LysM domains
External resourcesCAZypedia;
Statistics GenBank accession (74272); Uniprot accession (1523); PDB accession (35); 3D entries (22); cryst (0)
All (107369) Archaea (30) Bacteria (105158) Eukaryota (1045) Viruses (1101) unclassified (35) Structure (22) Characterized (50)
unclassified
Protein Name EC#OrganismGenBank UniprotPDB/3D
 UFOVP1246_62   freshwater metagenome CAB4193225.1    
 UFOVP667_10   freshwater metagenome CAB4155557.1    
 UFOVP667_10   freshwater metagenome CAB4155557.1    
 UFOVP546_3   freshwater metagenome CAB4149492.1    
 UFOVP419_53   freshwater metagenome CAB4141830.1    
 G08-26 (LysM)   uncultured organism ACY24838.1 D8VN53  
 KBTEX_01024 (Smc_1)   uncultured organism QEA04716.1    
 KBTEX_01069 (NlpD)   uncultured organism QEA04761.1    
 KBTEX_00302   uncultured organism QEA04001.1    
 KBTEX_01752 (Amic_4)   uncultured organism QEA05430.1    
 KBTEX_01610   uncultured organism QEA05290.1    
 KBTEX_01610   uncultured organism QEA05290.1    
 KBTEX_03887 (YneA)   uncultured organism QEA07529.1    
 KBTEX_03887 (YneA)   uncultured organism QEA07529.1    
 KBTEX_03887 (YneA)   uncultured organism QEA07529.1    
 KBTEX_03887 (YneA)   uncultured organism QEA07529.1    
 FLSS-26_0001   uncultured organism AGF93428.1    
 ORF   uncultured prokaryote CRY97897.1    
 Sequence 415 from patent US 7410647.   unidentified ACH29784.1    
 Sequence 415 from patent US 7410647.   unidentified ACH29784.1    
 Sequence 415 from patent US 7410647.   unidentified ACH29784.1    
 G3M56_000920   unidentified QQL45181.1    
 G3M56_000920   unidentified QQL45181.1    
 G3M56_000920   unidentified QQL45181.1    
 G3M56_000920   unidentified QQL45181.1    
 G3M56_012500   unidentified QQL44690.1    
 G3M56_012500   unidentified QQL44690.1    
 G3M56_012545   unidentified QQL44699.1    
 G3M56_012545   unidentified QQL44699.1    
 GO620_005925   unidentified QQL50988.1    
 GO620_015910   unidentified QQL51598.1    
 TM448A00172_0007   viral metagenome QJA45048.1    
 TM448B00344_0040   viral metagenome QJH95094.1    
 WWTP_pFosmid_7D_0021   wastewater metagenome CDL65439.1    
 WWTP_pFosmid_7D_0021   wastewater metagenome CDL65439.1    
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