Carbohydrate-Binding Module Family 50

Activities in FamilyModules of approx. 50 residues found attached to various enzymes from families GH18, GH19, GH23, GH24, GH25 and GH73, i.e. enzymes cleaving either chitin or peptidoglycan. Binding to chitopentaose demonstrated in the case of Pteris ryukyuensis chitinase A [Ohnuma T et al. (2008) J. Biol. Chem. 283:5178-87 (PMID: 18083709)]. CBM50 modules are also found in a multitude of other enzymes targeting the petidoglycan such as peptidases and amidases. These enzymes are not reported in the list below.
NoteAlso known as LysM domains
External resourcesCAZypedia;
Statistics GenBank accession (32450); Uniprot accession (1529); PDB accession (27); 3D entries (18); cryst (0)
All (46550) Archaea (12) Bacteria (45699) Eukaryota (444) Viruses (387) unclassified (8) Structure (18) Characterized (52)
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 N-acetylglucosaminidase / spore cortex-lytic enzyme (SleL;YaaH;BAS3402) 3.2.1.- Bacillus anthracis str. Sterne AAT55709.1
AJH43466.1
   
 N-acetylglucosaminidase / spore cortex-lytic enzyme (SleL;YaaH;BAS3402) 3.2.1.- Bacillus anthracis str. Sterne AAT55709.1
AJH43466.1
   
 cortical lytic enzyme / N-acetylglucosaminidase (CFLE;SleL) 3.2.1.- Bacillus cereus IFO13579 BAA92376.1 Q9K3E4  
 cortical lytic enzyme / N-acetylglucosaminidase (CFLE;SleL) 3.2.1.- Bacillus cereus IFO13579 BAA92376.1 Q9K3E4  
 spore cortex-specific N-acetylglucosaminidase (SleL;YaaH;BMQ_0021) 3.2.1.- Bacillus megaterium QM B1551 ADE67156.1
ABS32202.1
YP_003560590.1
A7LFH9
D5DUS2
4S3K[A]
 spore cortex-specific N-acetylglucosaminidase (SleL;YaaH;BMQ_0021) 3.2.1.- Bacillus megaterium QM B1551 ADE67156.1
ABS32202.1
YP_003560590.1
A7LFH9
D5DUS2
4S3K[A]
 autolysin 3.2.1.- Enterococcus faecalis AAA67325.1    
 autolysin 3.2.1.- Enterococcus faecalis AAA67325.1    
 autolysin 3.2.1.- Enterococcus faecalis AAA67325.1    
 autolysin 3.2.1.- Enterococcus faecalis AAA67325.1    
 autolysin 3.2.1.- Enterococcus faecalis AAA67325.1    
 N-acetylmuramidase (AtlC;EF1992) 3.2.1.17 Enterococcus faecalis V583 AAO81737.1
AAR58131.1
NP_815667.1
Q833G2  
 N-acetylmuramidase (AtlC;EF1992) 3.2.1.17 Enterococcus faecalis V583 AAO81737.1
AAR58131.1
NP_815667.1
Q833G2  
 N-acetylmuramidase (AtlB;EF0355) 3.2.1.17 Enterococcus faecalis V583 AAO80218.1
NP_814147.1
Q838S8  
 N-acetylmuramidase (AtlB;EF0355) 3.2.1.17 Enterococcus faecalis V583 AAO80218.1
NP_814147.1
Q838S8  
 N-acetylglucosaminidase (AtlA;EF0799;EF_0799) 3.2.1.- Enterococcus faecalis V583 AAO80613.1
AAR60023.1
NP_814543.1
P37710 2MKX[A]
 N-acetylglucosaminidase (AtlA;EF0799;EF_0799) 3.2.1.- Enterococcus faecalis V583 AAO80613.1
NP_814543.1
P37710  
 N-acetylglucosaminidase (AtlA;EF0799;EF_0799) 3.2.1.- Enterococcus faecalis V583 AAO80613.1
NP_814543.1
P37710  
 N-acetylglucosaminidase (AtlA;EF0799;EF_0799) 3.2.1.- Enterococcus faecalis V583 AAO80613.1
NP_814543.1
P37710  
 N-acetylglucosaminidase (AtlA;EF0799;EF_0799) 3.2.1.- Enterococcus faecalis V583 AAO80613.1
NP_814543.1
P37710  
 N-acetylglucosaminidase (AtlA;EF0799;EF_0799) 3.2.1.- Enterococcus faecalis V583 AAO80613.1
NP_814543.1
P37710  
 N-acetylglucosaminidase / β-1,4-N-acetylmuramoylhydrolase (Mur2;Mur-2) 3.2.1.17
3.2.1.96
Enterococcus hirae ATCC 9790 AAA24776.1 P39046  
 N-acetylglucosaminidase / β-1,4-N-acetylmuramoylhydrolase (Mur2;Mur-2) 3.2.1.17
3.2.1.96
Enterococcus hirae ATCC 9790 AAA24776.1 P39046  
 N-acetylglucosaminidase / β-1,4-N-acetylmuramoylhydrolase (Mur2;Mur-2) 3.2.1.17
3.2.1.96
Enterococcus hirae ATCC 9790 AAA24776.1 P39046  
 N-acetylglucosaminidase / β-1,4-N-acetylmuramoylhydrolase (Mur2;Mur-2) 3.2.1.17
3.2.1.96
Enterococcus hirae ATCC 9790 AAA24776.1 P39046  
 N-acetylglucosaminidase / β-1,4-N-acetylmuramoylhydrolase (Mur2;Mur-2) 3.2.1.17
3.2.1.96
Enterococcus hirae ATCC 9790 AAA24776.1 P39046  
 N-acetylglucosaminidase / β-1,4-N-acetylmuramoylhydrolase (Mur2;Mur-2) 3.2.1.17
3.2.1.96
Enterococcus hirae ATCC 9790 AAA24776.1 P39046  
 lytic transglycosylase (MltD;HP1572) 4.2.2.n1 Helicobacter pylori 26695 AAD08609.1
AFV42796.1
NP_208363.1
O26092  
 N-acetylglucosaminidase / peptidoglycan hydrolase (AcmA;llmg_0280) 3.2.1.96 Lactococcus lactis subsp. cremoris MG1363 AAC33367.1
AAB93629.1
CAA03037.1
CAL96887.1
A2RHZ5
Q48603
 
 N-acetylglucosaminidase / peptidoglycan hydrolase (AcmA;llmg_0280) 3.2.1.96 Lactococcus lactis subsp. cremoris MG1363 AAC33367.1
AAB93629.1
CAA03037.1
CAL96887.1
A2RHZ5
Q48603
 
 N-acetylglucosaminidase / peptidoglycan hydrolase (AcmA;llmg_0280) 3.2.1.96 Lactococcus lactis subsp. cremoris MG1363 AAC33367.1
AAB93629.1
CAA03037.1
CAL96887.1
A2RHZ5
Q48603
 
 peptidoglycan β-N-acetylglucosaminidase (AcmA;L68758) 3.2.1.- Lactococcus lactis subsp. lactis Il1403 AAK04370.1
NP_266428.1
Q9CIT4  
 peptidoglycan β-N-acetylglucosaminidase (AcmA;L68758) 3.2.1.- Lactococcus lactis subsp. lactis Il1403 AAK04370.1
NP_266428.1
Q9CIT4  
 peptidoglycan β-N-acetylglucosaminidase (AcmA;L68758) 3.2.1.- Lactococcus lactis subsp. lactis Il1403 AAK04370.1
NP_266428.1
Q9CIT4  
 peptidoglycan hydrolase (MurA;p66;Lmo2691) 3.2.1.- Listeria monocytogenes EGD-e CAD00904.1
NP_466213.1
Q8Y3Y8  
 peptidoglycan hydrolase (MurA;p66;Lmo2691) 3.2.1.- Listeria monocytogenes EGD-e CAD00904.1
NP_466213.1
Q8Y3Y8  
 peptidoglycan hydrolase (MurA;p66;Lmo2691) 3.2.1.- Listeria monocytogenes EGD-e CAD00904.1
NP_466213.1
Q8Y3Y8  
 peptidoglycan hydrolase (MurA;p66;Lmo2691) 3.2.1.- Listeria monocytogenes EGD-e CAD00904.1
NP_466213.1
Q8Y3Y8  
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 chitinase A (EaChiA) 3.2.1.14 Equisetum arvense BAI22848.1 C7G3I3 5BUM[A,B]
 chitinase / tRNase killer gammα-toxin (zymocin α-subunit) 3.2.1.14 Kluyveromyces lactis CAA25334.1
CAA25569.1
CAA30137.1
P09805  
 chitinase / tRNase killer gammα-toxin (zymocin α-subunit) 3.2.1.14 Kluyveromyces lactis CAA25334.1
CAA25569.1
CAA30137.1
P09805  
 chitinase A (ChiA;PrChiA) 3.2.1.14 Pteris ryukyuensis BAE98134.1 Q0WYK2  
 chitinase A (ChiA;PrChiA) 3.2.1.14 Pteris ryukyuensis BAE98134.1 Q0WYK2 4PXV[A,B,C,D]
Viruses
Protein Name EC#OrganismGenBank UniprotPDB/3D
 lysozyme 3.2.1.17 Bacillus phage PZA AAA88492.1 P07540  
 lysozyme 3.2.1.17 Bacillus phage PZA AAA88492.1 P07540  
 lysozyme (B103_15) 3.2.1.17 Bacillus virus B103 CAA67646.1
NP_690649.1
Q37896  
 lysozyme (B103_15) 3.2.1.17 Bacillus virus B103 CAA67646.1
NP_690649.1
Q37896  
 lysozyme 3.2.1.17 Bacillus virus phi29 AAA32288.1
AAA88347.1
ACE96038.1
CAA28632.1
B3VMQ1
P11187
 
 lysozyme 3.2.1.17 Bacillus virus phi29 AAA32288.1
AAA88347.1
ACE96038.1
CAA28632.1
B3VMQ1
P11187
 
 endolysin (Lyb5) 3.2.1.17 Lactobacillus phage phiPYB5 ABP88927.1 A5A5E0  
 endolysin (Lyb5) 3.2.1.17 Lactobacillus phage phiPYB5 ABP88927.1 A5A5E0  
 endolysin (Lyb5) 3.2.1.17 Lactobacillus phage phiPYB5 ABP88927.1 A5A5E0  
Top


Last update: 2017-10-09 © Copyright 1998-2017
AFMB - CNRS - Université d'Aix-Marseille