Carbohydrate-Binding Module Family 50

Known ActivitiesModules of approx. 50 residues found attached to various enzymes from families GH18, GH19, GH23, GH24, GH25 and GH73, i.e. enzymes cleaving either chitin or peptidoglycan. Binding to chitopentaose demonstrated in the case of Pteris ryukyuensis chitinase A [Ohnuma T et al. (2008) J. Biol. Chem. 283:5178-87 (PMID: 18083709)]. CBM50 modules are also found in a multitude of other enzymes targeting the petidoglycan such as peptidases and amidases. These enzymes are not reported in the list below.
NoteAlso known as LysM domains
External resourcesInterPro; PFAM;
Statistics GenBank accession (3148); Uniprot accession (1452); PDB accession (2); 3D entries (3); cryst (1)
All (5085) Archaea (3) Bacteria (4849) Eukaryota (149) Viruses (80) unclassified (4) Structure (3 - 1 cryst) Characterized (2)
Bacteria
Protein Name EC#OrganismGenBankUniprotPDB/3D
 N-acetylmuramidase (AtlC;EF1992) 3.2.1.17 Enterococcus faecalis V583 AAO81737.1
AAR58131.1
NP_815667.1
   
 N-acetylmuramidase (AtlC;EF1992) 3.2.1.17 Enterococcus faecalis V583 AAO81737.1
AAR58131.1
NP_815667.1
   

Footnotes

Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.





Last update: 2012-01-31 © Copyright 1998-2012
AFMB - CNRS - Universités Aix-Marseille I & II