Carbohydrate-Binding Module Family 50

Activities in FamilyModules of approx. 50 residues found attached to various enzymes from families GH18, GH19, GH23, GH24, GH25 and GH73, i.e. enzymes cleaving either chitin or peptidoglycan. Binding to chitopentaose demonstrated in the case of Pteris ryukyuensis chitinase A [Ohnuma T et al. (2008) J. Biol. Chem. 283:5178-87 (PMID: 18083709)]. CBM50 modules are also found in a multitude of other enzymes targeting the petidoglycan such as peptidases and amidases. These enzymes are not reported in the list below.
NoteAlso known as LysM domains
External resourcesCAZypedia;
Statistics GenBank accession (41990); Uniprot accession (1528); PDB accession (27); 3D entries (18); cryst (0)
All (59783) Archaea (13) Bacteria (58774) Eukaryota (532) Viruses (456) unclassified (8) Structure (18) Characterized (52)
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Ngar_c02110   Candidatus Nitrososphaera gargensis Ga9.2 AFU57159.1    
 Hbor_38640   Halogeometricum borinquense DSM 11551 ADQ69178.1 E4NVV8  
 halTADL_2216   halophilic archaeon True-ADL ATW88963.1    
 Halru_0130   Halovivax ruber XH-70 AGB14782.1    
 Metho_1619   Methanomethylovorans hollandica DSM 15978 AGB49813.1    
 MSHOH_1917   Methanosarcina horonobensis HB-1 = JCM 15518 AKB78400.1    
 MSWHS_1804   Methanosarcina sp. WWM596 AKB18667.1    
 Nmag_0771   Natrialba magadii ATCC 43099 ADD04356.1 D3SZZ8  
 B1756_04040   Natrialbaceae archaeon JW/NM-HA 15 ARS89004.1    
 NJ7G_0016   Natrinema sp. J7-2 AFO55272.1    
 NVIE_011430   Nitrososphaera viennensis EN76 AIC15373.1    
 ORF   uncultured archaeon AQS31177.1    
 BSM_26320   uncultured archaeon CBH39154.1 D1JAM4  

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