Carbohydrate-Binding Module Family 50

Activities in FamilyModules of approx. 50 residues found attached to various enzymes from families GH18, GH19, GH23, GH24, GH25 and GH73, i.e. enzymes cleaving either chitin or peptidoglycan. Binding to chitopentaose demonstrated in the case of Pteris ryukyuensis chitinase A [Ohnuma T et al. (2008) J. Biol. Chem. 283:5178-87 (PMID: 18083709)]. CBM50 modules are also found in a multitude of other enzymes targeting the petidoglycan such as peptidases and amidases. These enzymes are not reported in the list below.
NoteAlso known as LysM domains
External resourcesCAZypedia;
Statistics GenBank accession (74272); Uniprot accession (1523); PDB accession (35); 3D entries (22); cryst (0)
All (107369) Archaea (30) Bacteria (105158) Eukaryota (1045) Viruses (1101) unclassified (35) Structure (22) Characterized (50)
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Ngar_c02110   Candidatus Nitrososphaera gargensis Ga9.2 AFU57159.1    
 DV733_08195   Halapricum salinum CBA1105 QCC51224.1    
 Hbor_38640   Halogeometricum borinquense DSM 11551 ADQ69178.1 E4NVV8  
 G3I44_18610   Halogeometricum borinquense wsp4 QIB76104.1    
 halTADL_2216   halophilic archaeon True-ADL ATW88963.1    
 Halru_0130   Halovivax ruber XH-70 AGB14782.1    
 Metho_1619   Methanomethylovorans hollandica DSM 15978 AGB49813.1    
 MSHOH_1917   Methanosarcina horonobensis HB-1 = JCM 15518 AKB78400.1    
 MSWHS_1804   Methanosarcina sp. WWM596 AKB18667.1    
 HDBBLJII_00009   Methanosarcinales archaeon ANME-1 ERB6 QNO51312.1    
 EDLMLJLI_00024   Methanosarcinales archaeon ANME-1 ERB6 QNO51031.1    
 BICGGCBA_00025   Methanosarcinales archaeon ANME-1 ERB7 QNO57839.1    
 Nmag_0771   Natrialba magadii ATCC 43099 ADD04356.1 D3SZZ8  
 B1756_04040   Natrialbaceae archaeon JW/NM-HA 15 ARS89004.1    
 FGF80_01540   Natrinema pallidum BOL6-1 QCW02000.1    
 NJ7G_0016   Natrinema sp. J7-2 AFO55272.1    
 NVIE_011430   Nitrososphaera viennensis EN76 AIC15373.1    
 HC341_12900   Salinadaptatus halalkaliphilus 2447 QIT56019.1    
 HC341_03710   Salinadaptatus halalkaliphilus 2447 QIT54403.1    
 HC341_03710   Salinadaptatus halalkaliphilus 2447 QIT54403.1    
 HC341_03710   Salinadaptatus halalkaliphilus 2447 QIT54403.1    
 HC341_00330   Salinadaptatus halalkaliphilus 2447 QIT57058.1    
 HC341_10345   Salinadaptatus halalkaliphilus 2447 QIT55572.1    
 HC341_01390   Salinadaptatus halalkaliphilus 2447 QIT53986.1    
 ORF   uncultured archaeon AQS31177.1    
 BSM_26320   uncultured archaeon CBH39154.1 D1JAM4  
 ORF (fragment)   uncultured archaeon QBM02369.1    
 ORF (fragment)   uncultured archaeon QBM02369.1    
 ORF   uncultured archaeon QBM01973.1    
 ORF   uncultured archaeon QBM01973.1    

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