Carbohydrate-Binding Module Family 48

Known ActivitiesModules of approx. 100 residues with glycogen-binding function, appended to GH13 modules. Also found in the beta subunit (glycogen-binding) of AMP-activated protein kinases (AMPK)
Statistics GenBank accession (8378); Uniprot accession (2617); PDB accession (76); 3D entries (27); cryst (1)
All (7440) Archaea (74) Bacteria (6766) Eukaryota (573) unclassified (27) Structure (27 - 1 cryst) Characterized (152)
| 1 | 2 |
Archaea
Protein Name EC#OrganismGenBankUniprotPDB/3D
 maltooligosyltrehalose trehalohydrolase (TreZ;MTH) 3.2.1.141 Metallosphaera hakonensis JCM 8857 AAR18372.1 Q6SZP6  
 α-amylase / cyclomaltodextrinase (PFTA;PF1939) (Amy13) 3.2.1.1
3.2.1.54
Pyrococcus furiosus DSM 3638 AAL82063.1
CAZ78721.1
NP_579668.1
Q8TZP8 4AEF[A,B]
 α-amylase/maltooligosyltrehalose trehalohydrolase (TreZ) 3.2.1.1
3.2.1.141
Sulfolobus acidocaldarius BAA11011.1
BAA11863.1
Q53641  
 isoamylase (TreX) 3.2.1.68 Sulfolobus acidocaldarius ATCC33909 BAA11864.1 O05152  
 maltooligosyl trehalose trehalohydrolase (TreZ) 3.2.1.141 Sulfolobus shibatae AAF17553.1
AAM81589.1
Q9UWN9  
 glycogen debranching enzyme (TreX) 2.4.1.25
3.2.1.68
Sulfolobus shibatae B12 AAM81590.1 Q8NKQ3  
 α-amylase / maltooligosyltrehalose trehalohydrolase (GTHase) 3.2.1.1
3.2.1.141
Sulfolobus solfataricus KM1 AAR46454.1
BAA11010.1
Q55088 1EH9[A]
1EHA[A]
3VGB[A]
3VGD[A]
3VGE[A]
3VGF[A]
3VGG[A]
3VGH[A]
 isoamylase / 4-α-glucanotransferase (TreX;SSO2094;GlgX;ORF-c06_004;c06021) 2.4.1.25
3.2.1.68
Sulfolobus solfataricus P2 AAK42273.1
CAA69504.1
CAC23738.1
NP_343483.1
P95868
Q7LX99
2VNC[A,B]
2VR5[A,B]
2VUY[A,B]
 maltooligosyltrehalose trehalohydrolase (TreZ;MTHase;SSO2093;c06020) 3.2.1.141 Sulfolobus solfataricus P2 AAK42272.1
CAA69503.1
CAC23737.1
NP_343482.1
P95867  
 pullulanase type III (PulhA;Pul-Ta) 3.2.1.41 Thermococcus aggregans CAB94218.1
CAZ78888.1
Q9P9A0  
 amylopullulanase / pullulanase type III (Pul-Tk;TK-PUL;TK0977) 3.2.1.1
3.2.1.41
Thermococcus kodakarensis KOD1 BAD85166.1
CAT69621.1
CAZ78793.1
Q5JID9  
 cyclomaltodextrinase (Tocd;TON_1796) 3.2.1.54 Thermococcus onnurineus NA1 ACJ17286.1 B6YV58  
 cyclomaltodextrinase (CdnA) 3.2.1.133
3.2.1.54
Thermococcus sp. B1001 BAB18100.1
CAZ78887.1
Q9HHC8  
 cyclomaltodextrinase (CD;TcCD;CL1_0884) 3.2.1.54 Thermococcus sp. CL1 AFL95089.1    
 maltogenic α-amylase / cyclomaltodextrinase (TfMA;Tpen_1458) 3.2.1.133
3.2.1.54
Thermofilum pendens Hrk 5 ABL78855.1 A1S075  
Bacteria
Protein Name EC#OrganismGenBankUniprotPDB/3D
 maltooligosyltrehalose trehalohydrolase (TreZ) 3.2.1.141 Actinoplanes sp. SN223/29 ABV26726.1 A8QX08  
 branching-enzyme (GlgB) 2.4.1.18 Agrobacterium tumefaciens A348 AAD03472.1 P52979  
 pullulanase (PulAg) 3.2.1.41 Anaerobranca gottschalkii AAS47565.1 Q6QHE9  
 1,4-α-glucan branching enzyme (GlgB) 2.4.1.18 Anaerobranca gottschalkii CAJ38414.1 Q3BJY5  
 pullulanase 3.2.1.41 Anaerobranca horikoshii AAP45012.1 Q6XQ00  
 type I pullulanase (PulA) 3.2.1.41 Anoxybacillus sp. LM18-11 AEW23439.1   3WDH[A]
3WDI[A]
3WDJ[A]
 branching enzyme (GlgB;Aq_722) 2.4.1.18 Aquifex aeolicus VF5 AAC06895.1
CAE51854.1
NP_213496.1
O66936  
 malto-oligosyltrehalose trehalohydrolase (MTHase;TreZ) 3.2.1.141 Arthrobacter ramosus S34 BAB40766.1 Q9AJN6  
 maltooligosyltrehalose trehalohydrolase (TreZ) 3.2.1.141 Arthrobacter sp. Q36 AAE13738.1
AAE13730.1
AAE15470.1
AAE15478.1
BAA09668.1
Q44316  
 pullulanase (PulB) 3.2.1.41 Bacillus acidopullulyticus CAC60158.1
AAX00709.1
ACK18365.1
CAX87016.1
CAZ67879.1
CAZ67880.1
   
 pullulanase (PulA;BaPul13A) (Pul13A) 3.2.1.41 Bacillus acidopullulyticus CAC60156.1
AAX00707.1
ACK18363.1
CAX87014.1
  2WAN[A]
 branching-enzyme (GlgB) 2.4.1.18 Bacillus caldolyticus CAA78440.1 P30537  
 type II pullulanase A (PulA) 3.2.1.41 Bacillus cereus GXBC-3 AFP89962.1    
 type I pullulanase C (PulC) 3.2.1.41 Bacillus cereus GXBC-3 AFP89964.1    
 type I pullulanase B (PulB) 3.2.1.41 Bacillus cereus GXBC-3 AFP89963.1    
 branching enzyme 2.4.1.18 Bacillus cereus Q BAE96028.1 Q1AQI6  
 amylopullulanase (PulA) (partial) 3.2.1.41 Bacillus deramificans T89.117D AAE10887.1    
 isoamylase (BsIam) (fragment) 3.2.1.68 Bacillus sp. CICIM 263 AGA03915.1    
 alkaline amylase-pullulanase 3.2.1.1
3.2.1.41
Bacillus sp. KSM-1378 AAS36537.1
AAS36539.1
BAA11332.1
P70983  
 amylase-pullulanase (AapT) 3.2.1.1
3.2.1.41
Bacillus sp. XAL601 BAA05832.1 Q45643  
 branching-enzyme (GlgB;BSU30980) 2.4.1.18 Bacillus subtilis subsp. subtilis str. 168 AAC00214.1
CAA81040.1
CAB15076.1
NP_390976.1
P39118  
 pullulanase type I / glycogen-debranching enzyme (AmyX;BSU29930) 2.4.1.25
3.2.1.33
3.2.1.41
Bacillus subtilis subsp. subtilis str. 168 AAC00283.1
ACH14984.1
CAB14971.1
CAB14971.2
NP_390871.1
C0SPA0
O34587
2E8Y[A,B]
2E8Z[A,B]
2E9B[A,B]
 branching enzyme (GlgB) 2.4.1.18 Bergeriella denitrificans AAF04747.1
AAQ32649.1
AAT15256.1
CAC22097.1
Q9RQI5  
 bifunctional amylopullulanase (ApuB;Bbr_0123) 3.2.1.1
3.2.1.41
Bifidobacterium breve UCC2003 AAY89038.1
ABE94835.1
F9Y041  
 maltooligosyltrehalose trehalohydrolase (TreZ;BvMth) 3.2.1.141 Brevibacterium helvolum AAB95369.1 O52520  
 branching-enzyme (GlgB) 2.4.1.18 Butyrivibrio fibrisolvens H17C AAA23007.1 P30539  
 pullulanase type I (PulA) 3.2.1.41 Caldicellulosiruptor saccharolyticus AAB06264.1 Q59319  
 branching enzyme (GlgB;CPn0475) 2.4.1.18 Chlamydophila pneumoniae CWL029 AAD18615.1
NP_224671.1
   
 isoamylase (GlgX;Cgl2107;cg2310) 3.2.1.68 Corynebacterium glutamicum ATCC 13032 BAB99500.1
ACC05670.1
CAC25860.1
CAF20443.1
CAK31210.1
CCH25246.1
NP_601306.1
Q8NNT0  
 maltooligosyltrehalose trehalohydrolase(TreZ;Cgl2125;cg2333) 3.2.1.141 Corynebacterium glutamicum ATCC 13032 BAB99519.1
ACK11454.1
CAC25671.1
CAD43537.1
CAD88152.1
CAF20463.1
CCH25265.1
NP_601327.2
Q8NNR1  
 1,4-α-glucan branching enzyme (Glgb2) 2.4.1.18 Cyanobacterium sp. NBRC 102756 ABO93392.1 A4UU35  
 1,4-α-glucan branching enzyme (Glgb3) 2.4.1.18 Cyanobacterium sp. NBRC 102756 ABO93393.1 A4UU36  
 glycogen branching enzyme (GlgB;Dgeo_0981) 2.4.1.18 Deinococcus geothermalis DSM 11300 ABF45281.1 Q1IZQ3  
 malto-oligosyltrehalose trehalohydrolase (DR0464) 3.2.1.141 Deinococcus radiodurans R1 AAF10042.1
NP_294187.1
Q9RX51 2BHU[A]
2BHY[A]
2BHZ[A]
2BXY[A]
2BXZ[A]
2BY0[A]
2BY1[A]
2BY2[A]
2BY3[A]
 glycogen branching enzyme (GlgB;DR_1848;DR1848) 2.4.1.18 Deinococcus radiodurans R1 AAF11402.1
NP_295571.1
Q9RTB7  
 branching-enzyme (GlgB;b3432) 2.4.1.18 Escherichia coli K-12 MG1655 AAA23872.1
AAA58230.1
AAC76457.1
ABX94236.1
CAP11381.1
CAV00219.1
NP_417890.1
P07762 1M7X[A]
3O7Y[A,B,C,D]
3O7Z[A,B,C,D]
 isoamylase (GlgX;b3431) 3.2.1.68 Escherichia coli K-12 MG1655 AAC76456.1
AAA58229.1
AAA98735.1
CAP11380.1
NP_417889.1
P15067 2WSK[A]
 pullulanase (Pul3YH5) 3.2.1.41 Exiguobacterium acetylicum a1 / YH5 AFL46505.1    
 pullulanase I (PulA) 3.2.1.41 Fervidobacterium pennivorans VEN5 AAD30387.1 Q9XDB5 cryst
 isoamylase (Iam) 3.2.1.68 Flavobacterium sp. AAB63356.1 O32611  
 pullulanase (GK2827) 3.2.1.41 Geobacillus kaustophilus HTA426 BAD77112.1 Q5KW24  
 pullulanase (PulT) 3.2.1.41 Geobacillus stearothermophilus 1808262A    
 branching-enzyme (GlgB) 2.4.1.18 Geobacillus stearothermophilus 1503-4R AAA22482.1 P30538  
 α-glucan branching enzyme (GlgB) (fragment) 2.4.1.18 Geobacillus stearothermophilus CU21 CAA79749.1 Q59243  
 branching-enzyme (GlgB) 2.4.1.18 Geobacillus stearothermophilus TRBE14 BAA19588.1 Q59242  
 amylopullulanase (ApuTS) 3.2.1.1
3.2.1.41
Geobacillus stearothermophilus TS-23 AAG44799.1
CAZ78886.1
Q9EZZ4  
 pullulanase type I (Orf1) 3.2.1.41 Geobacillus thermoleovorans US105 CAC85704.1 Q8GJ67  
 pullulanase (PulA) 3.2.1.41 Klebsiella aerogenes W70 AAA25124.1
AAR52613.1
P07811 2FGZ[A]
2FH6[A]
2FH8[A]
2FHB[A]
2FHC[A]
2FHF[A]
 pullulanase A (PulA) 3.2.1.41 Klebsiella pneumoniae UNF5023 CAA36431.1
ACH14985.1
P07206 2YOC[A,B]
 maltooligosyltrehalose trehalohydrolase (TreZ) 3.2.1.141 Kocuria rosea QS412 AAY83363.1 Q4JQI8  
 amylopullulanase (ApuA) 3.2.1.1
3.2.1.41
Lactobacillus plantarum L137 BAF93906.1
BAG67031.1
A9EEQ2  
 branching-enzyme (GlgB;Rv1326c) 2.4.1.18 Mycobacterium tuberculosis H37Rv CAA98090.1
AFN49233.1
CCP44084.1
NP_215842.1
Q10625 3K1D[A]
 MYPU_6440 3.2.1.41 Mycoplasma pulmonis UAB CTIP CAC13817.1
NP_326475.1
Q98PS5  
 isoamylase 3.2.1.68 Myroides odoratus BAA82695.1 Q9RM63  
 maltooligosyltrehalose trehalohydrolase (TreZ) 3.2.1.141 Nostoc flagelliforme ADM32915.1 E1ANS4  
 maltooligosyltrehalose trehalohydrolase (TreZ) 3.2.1.141 Nostoc punctiforme IAM M-15 BAG85336.1 B6ZIU9  
 isoamylase (GlgX) 3.2.1.68 Pectobacterium carotovorum subsp. carotovorum LY34 ABV71062.1
ACN29676.1
A9XZV3
C0JID0
 
 glycogen branching enzyme (GlgB) 2.4.1.18 Pectobacterium carotovorum subsp. carotovorum LY34 ACN29675.1 C0JIC9  
 isoamylase (Iam;IsoA) 3.2.1.68 Pseudomonas amyloderamosa SB-15 AAA25854.1 P10342 1BF2[A]
 isoamylase (Iam) 3.2.1.68 Pseudomonas sp. AAA25855.1
AAQ71617.1
AAQ71618.1
CAA00929.1
P26501  
 pullulanase 3.2.1.41 Pullulanibacillus naganoensis AAQ80298.1
AAQ80294.1
AAQ80299.1
AAQ80300.1
AEV53626.1
   
 Malto-oligosyltrehalose trehalohydrolase 3.2.1.141 Rhizobium sp. M-11 AAE13737.1
AAE13729.1
AAE15469.1
AAE15477.1
BAA11187.1
Q53238  
 isoamylase 3.2.1.68 Rhodothermus marinus AAN89211.1
AAE45696.1
AAE45700.1
AAN89215.1
   
 branching enzyme (GlgB;RoBE) 2.4.1.18 Rhodothermus marinus JCM9785 BAB69858.1
AAR45540.1
Q93HU3  
 α-amylase (AmyB) (Amy13A) 3.2.1.1 Roseburia sp. A2-194 CAJ20070.1 Q3LB10  
 pullulanase type I (Sap;BibA;SAG1216;SAG_1216) 3.2.1.41 Streptococcus agalactiae 2603V/R serotype V AAN00098.1
NP_688225.1
   
 pullulanase (SpuA) 3.2.1.41 Streptococcus pneumoniae 3.B AAG33958.1 Q9F930  
 glycogen-degrading enzyme (SpuA;PulA;SP0268) 3.2.1.- Streptococcus pneumoniae TIGR4 AAK74446.1
AAT16713.1
ACK14503.1
ACW45222.1
NP_344806.1
Q97SQ7 2YA0[A]
2YA1[A]
2YA2[A]
 Spy49_1626c (PulA) 3.2.1.41 Streptococcus pyogenes NZ131 ACI61883.1
CAD32942.1
B5XIM1
Q8KLP1
 
 bifunctional amylopullulanase (ApuA;SSU1849) 3.2.1.1
3.2.1.41
Streptococcus suis P1/7 CAR47543.1 C5VVZ9  
 branching-enzyme 2.4.1.18 Streptomyces aureofaciens AAA67437.1 P52980  
 branching enzyme I (GlgBI;SC6A11.16c;SCO5440) 2.4.1.18 Streptomyces coelicolor A3(2) CAA58314.1
CAA04603.1
CAB72416.1
NP_629578.1
Q59833  
 branching enzyme II (GlgBII;SC4G10.11c;SCO7332) 2.4.1.18 Streptomyces coelicolor A3(2) CAB92878.1
CAA52109.1
NP_631386.1
Q59832  
 isoamylase (GlgX;Synpcc7942_0086) 3.2.1.68 Synechococcus elongatus PCC 7942 ABB56118.1 Q31S51  
 isoamylase (Tfu_1891) 3.2.1.68 Thermobifida fusca YX AAZ55924.1 Q47NP5  
 pullulanase (PulA;Tm1845) (Pul13A) 3.2.1.41 Thermotoga maritima MSB8 AAD36907.1
AAM56795.1
ABJ38302.1
ABJ38322.1
ACW20067.1
ACW20078.1
AGL50777.1
AHD18265.1
CAA04522.1
CAH68696.1
CAT81460.1
NP_229641.1
G4FGN0
O33840
 
 pullulanase (PulA) 3.2.1.41 Thermotoga neapolitana KCCM 41025 ACN58254.1 C0LLG9  
 pullulanase (Pul) 3.2.1.41 Thermus sp. IM6501 AAC15073.1 O69008  
 pullulanase (Pul) 3.2.1.41 Thermus thermophilus HB8 BAB62095.1 Q7DI19  
 α-1,4-glucan branching enzyme (AmyB) 2.4.1.18 uncultured bacterium AAP70397.1 Q6XE44  
 α-1,4-glucan branching enzyme (GlgB;YPO3942) 2.4.1.18 Yersinia pestis CO92 Biovar Orientalis CAC93404.1
CAL22523.1
NP_407383.1
Q8ZA75  
 α-1,4-glucan branching enzyme (GlgB;y3886) 2.4.1.18 Yersinia pestis KIM AAM87431.1
NP_671180.1
   
Eukaryota
Protein Name EC#OrganismGenBankUniprotPDB/3D
 pullulanase / isoamylase (Lda;AtPU1;AtLDA;LDA1;At5g04360) 3.2.1.41
3.2.1.68
Arabidopsis thaliana AAO00771.1
AED90732.1
NP_196056.1
Q8GTR4  
 branching-enzyme 2 (BE2;Sbe2-1;Sbe2.1;At2g36390) 2.4.1.18 Arabidopsis thaliana AAD24644.1
AAB03099.1
AAM97077.1
ABC04873.1
AEC09247.1
BAE98973.1
CAA04134.1
NP_181180.1
O23647
Q42526
 
 branching-enzyme 3 (BE3;sbe2-2;sbe2.2;At5g03650) 2.4.1.18 Arabidopsis thaliana CAB82930.1
AAB03100.1
ABC04874.1
AED90637.1
NP_195985.1
Q42531
Q9LZS3
 
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Footnotes

Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.





Last update: 2014-11-13 © Copyright 1998-2014
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