Carbohydrate-Binding Module Family 47

Activities in FamilyModules of approx 150 residues. Fucose-binding activity demonstrated
3D Structure Statusβ-sandwich
NoteCreated from Boraston, Wang and Burke (2006) J. Biol. Chem., 281:35263-71 (PMID: 16987809)
Statistics GenBank accession (1163); Uniprot accession (2); PDB accession (14); 3D entries (7); cryst (0)
Bacteria
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 lectinolysin / human platelet aggregation factor (LLY;Sm-hPAF;samhpaf)   Streptococcus mitis Nm-65 BAE72438.1
BBA91466.1
 
4GWI[A] α-L-Fucp-(1-2)-β-D-Galp-(1-4)[α-L-Fucp-(1-3)]-β-D-GlcpNAc
1.60
4GWJ[A] α-L-Fucp-(1-2)-β-D-Galp-(1-3)[α-L-Fucp-(1-4)]-β-D-GlcpNAc
1.60
 endo-β-1,4-galactosidase (SP_2159;SP2159;Sp4GH98) (LewisY-specific)   Streptococcus pneumoniae TIGR4 AAK76213.1
NP_346573.1
A0A0H2US34
Q97N96
2J22[A] 1.8
 endo-β-1,4-galactosidase (SP_2159;SP2159;Sp4GH98) (LewisY-specific)   Streptococcus pneumoniae TIGR4 AAK76213.1
AAY71778.1
NP_346573.1
A0A0H2US34
Q97N96
2J1R[A,B] 1.54
2J1S[A,B] β-L-Fucp
1.5
2J1T[A,B] α-L-Fucp-(1-2)-β-D-Galp-(1-4)[α-L-Fucp-(1-3)]-β-D-GlcpNAc
1.6
2J1U[A,B] α-D-GalpNAc-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp-(1-4)-β-D-Glcp
1.8
2J1V[A,B] α-L-Fucp-(1-2)-β-D-Galp-(1-4)-β-D-GlcpNAc
1.45
 lectinolysin (Lly)   Streptococcus sp. SK597 ACE79194.1  
3LE0[A] 1.91
3LEG[A] α-L-Fucp-(1-2)-β-D-Galp-(1-4)[α-L-Fucp-(1-3)]-β-D-GlcpNAc
2.01
3LEI[A] β-L-Fucp
1.90
3LEK[A] α-L-Fucp-(1-2)-β-D-Galp-(1-3)[α-L-Fucp-(1-4)]-α-D-GlcpNAc
2.00
Eukaryota
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 fucolectin   Anguilla anguilla    
1K12[A] α-L-Fucp
1.90
 F-lectin (FBP32;MsaFBP32;MS-FBP32)   Morone saxatilis ABB29997.1
ABB29989.1
ACQ18748.1
 
3CQO[A,B,C] α-L-Fucp
2.32
 F-lectin (FBP32;MsaFBP32;MS-FBP32)   Morone saxatilis ABB29997.1
ABB29989.1
ACQ18748.1
 
3CQO[A,B,C] α-L-Fucp
2.32
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