Carbohydrate-Binding Module Family 41

Known ActivitiesModules of approx. 100 residues found in primarily in bacterial pullulanases. The N-terminal module from Thermotoga maritima Pul13 has been shown to bind to the α-glucans amylose, amylopectin, pullulan, and oligosaccharide fragments derived from these polysaccharides (Lammerts van Bueren et al. (2004) Biochemistry 43:15633-42) (PMID: 15581376).
NoteFormerly known as X28 modules.
Statistics GenBank accession (226); Uniprot accession (90); PDB accession (16); 3D entries (8); cryst (1)
All (251) Bacteria (244) Eukaryota (3) unclassified (4) Structure (8 - 1 cryst) Characterized (27)
Bacteria
Protein Name EC#OrganismGenBankUniprotPDB/3D
 acarbose resistent α-amylase (AcbE) 3.2.1.1 Actinoplanes sp. SE50/110 CAJ81030.1 Q27GR6  
 acarbose resistent α-amylase (AcbE) 3.2.1.1 Actinoplanes sp. SE50/110 CAJ81030.1 Q27GR6  
 α-amylase (AcbE) 3.2.1.1 Actinoplanes sp. SE50/110 CAC02970.1 Q9K5L6  
 pullulanase (PulAg) 3.2.1.41 Anaerobranca gottschalkii AAS47565.1 Q6QHE9  
 pullulanase 3.2.1.41 Anaerobranca horikoshii AAP45012.1 Q6XQ00  
 pullulanase (PulB) 3.2.1.41 Bacillus acidopullulyticus AAX00709.1
ACK18365.1
CAC60158.1
CAX87016.1
CAZ67879.1
CAZ67880.1
   
 pullulanase (PulA) (Pul13A) 3.2.1.41 Bacillus acidopullulyticus AAX00707.1
ACK18363.1
CAC60156.1
CAX87014.1
  2WAN[A]
 Sequence 11 from patent US 5817498 3.2.1.41 Bacillus deramificans T89.117D AAE10887.1    
 alkaline amylase-pullulanase 3.2.1.1
3.2.1.41
Bacillus sp. KSM-1378 AAS36537.1
AAS36538.1
BAA11332.1
P70983  
 alkaline amylase-pullulanase 3.2.1.1
3.2.1.41
Bacillus sp. KSM-1378 AAS36537.1
BAA11332.1
P70983  
 alkaline amylase-pullulanase 3.2.1.1
3.2.1.41
Bacillus sp. KSM-1378 AAS36537.1
BAA11332.1
P70983  
 bifunctional amylopullulanase (ApuB) 3.2.1.1
3.2.1.41
Bifidobacterium breve UCC2003 AAY89038.1    
 bifunctional amylopullulanase (ApuB) 3.2.1.1
3.2.1.41
Bifidobacterium breve UCC2003 AAY89038.1    
 pullulanase I (PulA) 3.2.1.41 Fervidobacterium pennivorans VEN5 AAD30387.1 Q9XDB5 cryst
 pullulanase (PulA) 3.2.1.41 Klebsiella aerogenes W70 AAA25124.1
AAR52613.1
P07811.1 2FGZ[A]
2FH6[A]
2FH8[A]
2FHB[A]
2FHC[A]
2FHF[A]
 pullulanase A (PulA) 3.2.1.41 Klebsiella pneumoniae UNF5023 ACH14985.1
CAA36431.1
P07206.2  
 α-amylase 3.2.1.1 Micrococcus sp. 207 CAA39321.1 Q06812  
 α-amylase 3.2.1.1 Micrococcus sp. 207 CAA39321.1 Q06812  
 pullulanase 3.2.1.41 Pullulanibacillus naganoensis AAQ80294.1
AAQ80298.1
AAQ80299.1
   
 pullulanase (Sap;SAG1216;SAG_1216) 3.2.1.41 Streptococcus agalactiae 2603V/R serotype V AAN00098.1
NP_688225.1
  3FAW
3FAX
 pullulanase (Sap;SAG1216;SAG_1216) 3.2.1.41 Streptococcus agalactiae 2603V/R serotype V AAN00098.1
NP_688225.1
  3FAW
3FAX
 pullulanase (SpuA) 3.2.1.41 Streptococcus pneumoniae 3.B AAG33958.1 Q9F930  
 pullulanase (SpuA) 3.2.1.41 Streptococcus pneumoniae 3.B AAG33958.1 Q9F930  
 Spy49_1626c (PulA) 3.2.1.41 Streptococcus pyogenes NZ131 ACI61883.1
CAD32942.1
B5XIM1
Q8KLP1
 
 Spy49_1626c (PulA) 3.2.1.41 Streptococcus pyogenes NZ131 ACI61883.1
CAD32942.1
B5XIM1
Q8KLP1
 
 α-amylase (Amy) 3.2.1.1 Streptomyces lividans TK24 CAA49759.1 Q05884  
 pullulanase (PulA;Tm1845) (Pul13A) 3.2.1.41 Thermotoga maritima MSB8 AAD36907.1
AAM56795.1
ABJ38302.1
ABJ38322.1
ACW20067.1
ACW20078.1
CAA04522.1
CAH68696.1
CAT81460.1
NP_229641.1
O33840.2 2J71[A]
2J72[A,B]
2J73[A,B]

Footnotes

Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.