Activities in Family	The granular starch-binding function has been demonstrated in several cases. Interact strongly with cyclodextrins. Often designated as starch-binding domains (SBD).
Note	PDB:1b90
External resources	CAZypedia; HOMSTRAD; PROSITE;
Statistics	GenBank accession (3795); Uniprot accession (137); PDB accession (86); 3D entries (19); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
β-amylase (SpoII)		Bacillus cereus VAR. MYCOIDES	BAA34650.1 BAA75890.1	P36924 Q9Z4N9	1B90[A] 2.50 1B9Z[A] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-β-D-Glcp 2.10 1CQY[A] 1.95 1ITC[A] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp 2.10 1ITD[nd] 1ITJ[nd] 1J0Y[A,B,C,D] β-D-Glcp 2.10 1J0Z[A,B,C,D] α-D-Glcp-(1-4)-β-D-Glcp 2.20 1J10[A,B,C,D] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Xylp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Xylp 2.10 1J11[A,B,C,D] 2.00 1J12[A,B,C,D] 2.10 1J18[A] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-β-D-Glcp 2.00 1VEM[A] α-D-Glcp-(1-4)-α-D-Glcp 1.85 1VEN[A] α-D-Glcp D-1-deoxy-Glcp 2.02 1VEO[A] α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-β-D-Glcp 2.12 1VEP[A] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-β-D-Glcp 2.06 5BCA[A,B,C,D] 2.20
β-cyclodextrin glucanotransferase (Cgt)		Bacillus sp. 1011	AAA22308.1	P05618	1D7F[A] 1.90 1DED[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp 2.00 1I75[A] <carb_like_NOJ> 2.00 1PAM[A] 1.80 1UKQ[A,B] α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-β-D-Glcp 2.00 1UKS[A,B] α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-β-D-Glcp 1.90 1UKT[A,B] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp 2.20 1V3J[A,B] 2.00 1V3K[A,B] 2.00 1V3L[A,B] α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-β-D-Glcp 2.10 1V3M[A,B] α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-β-D-Glcp β-D-Glcp 2.00
g-cyclodextrin glucanotransferase (Cgt)		Evansella clarkii 7364	BAH14968.1 ABC06412.1 BAB91217.1 BAB91217.2 CAD87625.1	B9A1J6 Q8L3E0	4JCM[A] 1.65
maltogenic α-amylase (BSuA;Novamyl)		Geobacillus stearothermophilus C599	ABA38666.1 AAA22233.1 AAE62848.1 AAE62849.1 AAY11155.1 ALJ77020.1 CAL60144.1 CAZ67881.1	P19531	1QHO[A] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp1N-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp 1.70 1QHP[A] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-β-D-Glcp 1.70
a/β-cyclodextrin glucanotransferase (Cgt;CgtS;Aga2)		Geobacillus stearothermophilus No. 2 / NO2	CAA41770.1 CAA41771.1 CAA41772.1	P31797	1CYG[A] 2.50
β-cyclodextrin glucanotransferase (Cgt)		Niallia circulans 251	CAA55023.1	P43379	1CDG[A] α-D-Glcp-(1-4)-α-D-Glcp 2.00 1CGV[A] α-D-Glcp-(1-4)-α-D-Glcp 2.50 1CGW[A] α-D-Glcp-(1-4)-α-D-Glcp 2.50 1CGX[A] α-D-Glcp-(1-4)-α-D-Glcp 2.50 1CGY[A] α-D-Glcp-(1-4)-α-D-Glcp 2.50 1CXE[A] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp 2.10 1CXF[A] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp a-cyclodextrin 2.10 1CXH[A] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp 2.41 1CXI[A] α-D-Glcp-(1-4)-α-D-Glcp 2.20 1CXK[A] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp 2.09 1CXL[A] α-D-4-deoxy-Glcp-(1-4)-α-D-Glcp α-D-4-deoxy-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp1F α-D-4-deoxy-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp-(1-4)-ASP 1.81 1D3C[A] α-D-Glcp-(1-4)-α-D-Glcp 1.78 1DTU[A] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp 2.40 1EO5[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp 2.00 1EO7[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp 2.48 1KCK[A] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp 2.43 1KCL[A] α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp β-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp 1.94 1OT1[A] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp 2.00 1OT2[A] α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp 2.10 1PEZ[A] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp α-D-Glcp-(1-4)-β-D-Glcp 2.32 1PJ9[A] α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp α-D-Glcp-(1-4)-β-D-Glcp 2.00 1TCM[A,B] 2.20 2CXG[A] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp 2.50 2DIJ[A] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp 2.60
β-cyclodextrin glucanotransferase (CGTase)		Niallia circulans 8	CAA48401.1	P30920	1CGT[A] 2.00 1CGU[A] α-D-Glcp-(1-4)-β-D-Glcp-(1-4)-GLU 2.50 3CGT[A] b-cyclodextrin 2.40 4CGT[A] 2.60 5CGT[A] α-D-Glcp α-D-Glcp-(1-4)-β-D-Glcp 2.50 6CGT[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp 2.60 7CGT[A] 3.00 8CGT[A] α-D-Glcp-(1-4)-α-D-Glcp4S-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp4S-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp4S 2.40 9CGT[A] α-D-Glcp-(1-4)-α-D-Glcp4S-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp4S-(1-4)-α-D-Glcp1S 2.50
α-cyclodextrin glucanotransferase		Paenibacillus macerans 602-1	AGT21379.1	P04830 S5ZJ19	3WMS[A] 2.30 6L2H[A] 2.10
α-cyclodextrin glucanotransferase (CD;Cgt;CgtM)		Paenibacillus macerans IAM1243/ IB7 / IFO 3490 (NRRL B-388) / JFB05-01 (CCTCC M203062)	CAA41773.1 AAA22298.1 AAC04359.1	O52766 P04830	4JCL[A] 1.70 6AIJ[A] 2.10
maltotetraose-forming amylase (MTA;PSA)		Roseateles saccharophilus IAM1504	CAA34708.1 ABN31435.1 ABN31436.1 ABN31437.1 ABN31438.1 ABN31439.1 ABN31440.1 ABN31441.1 ABN31443.1	P22963	7CZJ[A,B] 1.50
a/β-cyclodextrin glucanotransferase (AmyA)		Thermoanaerobacterium thermosulfurigenes EM1	AAB00845.1	P26827	1A47[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp 2.56 1CIU[A] 2.30 3BMV[A] 1.60 3BMW[A] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp 1.60
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
glucoamylase P (GamP)		Amorphotheca resinae ATCC 20495	CAA47945.1 ABL22822.1 CAA48243.1 CAY05396.1	Q03045	6FHW[A,B] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp 3.60
glucoamylase (partial)		Aspergillus niger B1	AAM18050.2		5GHL[A,B,C,D] 2.00
glucoamylase (GlaA;An03g06550)		Aspergillus niger CBS 513.88	CAK38411.1 AAP60775.1 AAT67041.1 ABL16522.1 ACJ91357.1 ACP59407.1 ADX86749.1 AEE60909.1 CAA25219.1 CAA25303.1 CAY05387.1	A2QHE1 F1DHX7 P69328 Q6DNH5	1AC0[A] NMR 1ACZ[A] NMR 1KUL[A] NMR 1KUM[A] NMR
laforin / Hs-laforin (Epm2a)		Homo sapiens	AAG18377.1 AAC83347.2 AAH70047.1 AAW18454.1 ACW03513.1 BAG51107.1 CAA10199.1 CAI20057.1 CAI21419.1 CAI21420.1 CAI21675.1 CAI21676.1 CAI21677.1 NP_005661.1		4RKK[A,C] α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-D-1-deoxy-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-D-1-deoxy-Glcp 2.40
genethonin 1 (STBD1)		Homo sapiens	AAH22301.1 AAC78827.1 BAG51020.1 BAG52246.1 BAG52516.1 BAG53961.1 BAG59080.1 CAE90084.1 NP_003934.1		8X8K[A,B,C,D]
glycerophosphodiester phosphodiesterase 5 (Gde5;KIAA1434;FLJ11085)		Homo sapiens	AAH27588.1 BAA92672.2 CAB91047.2 CAD83808.1 NP_062539.1		2Z0B[A,B,C,D,E,F] 2.00
glucoamylase (PoGA;PDE_05527)		Penicillium oxalicum 114-2	EPS30575.1	S7ZIW0	6FHV[A] 2.00
glucoamylase (GA; TGA; TrGA)		Trichoderma reesei			2VN4[A] 1.85 2VN7[A] 1.90
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