Carbohydrate-Binding Module Family 1

Activities in FamilyModules of approx. 40 residues found almost exclusively in fungi. The cellulose-binding function has been demonstrated in many cases, and appears to be mediated by three aromatic residues separated by about 10.4 angstrom and which form a flat surface. The only non-fungal occurence of CBM1 is in an algal non-hydrolytic polysaccharide-binding protein which is composed of four repeated CBM1 modules. Binding to chitin has been demonstrated in one case.
NotePreviously known as cellulose-binding domain family I (CBD I).
External resourcesPROSITE; SMART;
Statistics GenBank accession (1214); Uniprot accession (331); PDB accession (20); 3D entries (5); cryst (1)
All (1047) Bacteria (1) Eukaryota (1040) Viruses (1) unclassified (5) Structure (5 - 1 cryst) Characterized (217)
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Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 PIIN_07887   Serendipita indica DSM 11827 CCA73934.1    
 PIIN_08402   Serendipita indica DSM 11827 CCA74449.1    
 PIIN_08751 (fragment)   Serendipita indica DSM 11827 CCA74782.1    
 PIIN_10600 (fragment)   Serendipita indica DSM 11827 CCA76609.1    
 PIIN_10672 (fragment)   Serendipita indica DSM 11827 CCA76684.1    
 PIIN_11387 (fragment)   Serendipita indica DSM 11827 CCA77410.1    
 PIIN_10610   Serendipita indica DSM 11827 CCA76619.1    
 PIIN_03737   Serendipita indica DSM 11827 CCA69796.1    
 PIIN_03737   Serendipita indica DSM 11827 CCA69796.1    
 PIIN_11381   Serendipita indica DSM 11827 CCA77404.1    
 PIIN_07886   Serendipita indica DSM 11827 CCA73933.1    
 SMAC_02223   Sordaria macrospora k-hell CBI53519.1    
 cellobiose dehydrogenase (CdhIIA1)   Stachybotrys bisbyi DSM 630.42 ADT70777.1    
 cellobiose dehydrogenase (CdhIIA2) 1.1.99.18 Stachybotrys bisbyi DSM 630.42 ADT70778.1    
 Man5B   Staphylotrichum coccosporum D AKT45098.1    
 endo-β-1,4-glucanase (Stce1) 3.2.1.4 Staphylotrichum coccosporum IFO 31817 BAG69187.1 B5BNY1  
 cellobiohydrolase 1 (Cbh1)   Stereum hirsutum AFH78149.1    
 cellobiohydrolase (Cel6A) 3.2.1.91 Stilbella annulata CAH05678.1    
 endoglucanase (CBH I) 3.2.1.4 Syncephalastrum racemosum BCC18080 ABU49185.2 A7UGD9  
 β-glucosidase 2, partial (BgL)   Talaromyces amestolkiae CIB AKK32386.1    
 cellobiohydrolase II (Acc2) (Cel6A) 3.2.1.91 Talaromyces cellulolyticus CF-2612 AAE50824.1
BAA74458.1
O93837  
 ACHi-29 (short fragment)   Talaromyces cellulolyticus CF-2612 BAN09067.1    
 endo-β-1,4-xylanase 10A (Xyl10A) 3.2.1.8 Talaromyces cellulolyticus CF-2612 BAN82655.1    
 xylanase 11B (XylB;TcXylB) 3.2.1.8 Talaromyces cellulolyticus CF-2612 BAO51920.1    
 xylanase 11F (XylF;TcXylF) 3.2.1.8 Talaromyces cellulolyticus CF-2612 BAO51924.1    
 feruloyl esterase B (FaeB;TcFAE)   Talaromyces cellulolyticus CF-2612 BAP90855.1   cryst
 acetylxylan esterase (Axe;TcAXE;TcAE206) 3.1.1.6 Talaromyces cellulolyticus CF-2612 BAP90856.1    
 ORF   Talaromyces cellulolyticus CF-2612 BAP90857.1    
 cellobiohydrolase I / 7A (TCE0_004r00180) (Cel7A) 3.2.1.176 Talaromyces cellulolyticus Y-94 GAM33347.1    
 β-glucosidase 3A (TCE0_039f12945) (Bgl3A) 3.2.1.21 Talaromyces cellulolyticus Y-94 GAM40530.1    
 endo-β-1,4-glucanase 5A (TCE0_013f01292) (Cel5A) 3.2.1.4 Talaromyces cellulolyticus Y-94 GAM33994.1    
 endo-β-1,4-glucanase 7B (TCE0_024r07350) (Cel7B) 3.2.1.4 Talaromyces cellulolyticus Y-94 GAM37432.1    
 endo-β-1,4-xylanase 10A (TCE0_023r06982) (partial) (Xyl10A)   Talaromyces cellulolyticus Y-94 GAM37231.1    
 ferulic acid esterase A (FaeA)   Talaromyces funiculosus CAC85738.1 Q8WZI7  
 cellulase   Talaromyces funiculosus ACH91035.1 B5TMG4  
 endo-β-1,4-xylanase B (XynB) 3.2.1.8 Talaromyces funiculosus 8/403 CAD33900.1 Q8J0K5  
 endo-β-1,4-xylanase D (XynD) 3.2.1.8 Talaromyces funiculosus 8/403 CAG25554.1 Q5ZNB1  
 α-L-arabinofuranosidase (AbfB2;AbfB-2;PfAbfB2) 3.2.1.55 Talaromyces funiculosus 8/403 CAL85369.1    
 cellobiohydrolase (XynA) 3.2.1.176 Talaromyces funiculosus IMI 378536 CAC85737.1 Q8WZJ4  
 cinnamoyl esterase (FaeB) 3.1.1.- Talaromyces funiculosus IMI134756 CAC14144.1
AAP60304.1
Q9HE18  
 cellobiohydrolase I (Cbh1) 3.2.1.176 Talaromyces funiculosus NCL1 ADX60067.1    
 GH6   Talaromyces leycettanus CBS 398.68 CDF76448.1    
 GH7   Talaromyces leycettanus CBS 398.68 CDF76456.1    
 β-mannanase (Man5A) 3.2.1.78 Talaromyces leycettanus JCM12802 AJF11663.1    
 endo-β-1,4-glucanase 5 (Eng5) 3.2.1.4 Talaromyces pinophilus KMJ601 ACN43345.1 C0L2S4  
 cellulase   Talaromyces pinophilus WT10 AKU20093.1    
 endoglucanase (Cel7B)   Talaromyces purpureogenus AEL78899.1    
 cellobiohydrolase (Cel7A)   Talaromyces purpureogenus HZ11 AEL78900.1    
 acetyl xylan esterase (AxeI;AcXEI) 3.1.1.72 Talaromyces purpureogenus MYA-38 AAM93261.1 Q8NJP6  
 celloobiohydrolase II (CbhII)   Talaromyces verruculosus APE61639.1    
 xylanase (XynE;PfXynE) 3.2.1.8 Talaromyces versatilis 8/403 AHI42056.1    
 cellobiose dehydrogenase (fragment)   Termitomyces clypeatus AOW70087.1    
 GH45 (fragment)   Thermomucor indicae-seudaticae CBS 104.75 CDF76459.1    
 LPMO9B, MtLPMO9B   Thermothelomyces thermophila AON76800.1    
 xylanase (Xyn2;SfXyn2;Xyl3;MYCTH_112050) 3.2.1.8 Thermothelomyces thermophila ATCC 42464 AEO60457.1    
 cellobiose dehydrogenase (Cdh;MYCTH_111388) 1.1.99.18 Thermothelomyces thermophila ATCC 42464 AEO58137.1
AAC26221.1
O74240  
 MYCTH_110651   Thermothelomyces thermophila ATCC 42464 AEO54509.1    
 cellobiohydrolase (Cbh2b;ClCbh2;MYCTH_66729)   Thermothelomyces thermophila ATCC 42464 AEO55787.1    
 MYCTH_111088   Thermothelomyces thermophila ATCC 42464 AEO56416.1    
 β-glycan-cleaving enzyme (StCel61a;MYCTH_46583) (Cel61A)   Thermothelomyces thermophila ATCC 42464 AEO56542.1 G2Q9T3  
 endo-β-1,4-glucanase (Eg7a;MtEG7a;MYCTH_111372) 3.2.1.4 Thermothelomyces thermophila ATCC 42464 AEO58196.1    
 MYCTH_2066457   Thermothelomyces thermophila ATCC 42464 AEO60460.1    
 MYCTH_98003   Thermothelomyces thermophila ATCC 42464 AEO60934.1    
 MYCTH_112399   Thermothelomyces thermophila ATCC 42464 AEO62076.1    
 endo-β-1,4-glucanase (EG II;StCel5A;MYCTH_86753) (Cel5A) 3.2.1.4 Thermothelomyces thermophila ATCC 42464 AEO53769.1
AEM23898.1
   
 MYCTH_109566   Thermothelomyces thermophila ATCC 42464 AEO55544.1    
 xylanase (Xyl7;MYCTH_100068) 3.2.1.8 Thermothelomyces thermophila ATCC 42464 AEO57157.1    
 MYCTH_80312   Thermothelomyces thermophila ATCC 42464 AEO58169.1    
 MYCTH_101354 (fragment)   Thermothelomyces thermophila ATCC 42464 AEO58207.1    
 MYCTH_33936 (fragment)   Thermothelomyces thermophila ATCC 42464 AEO60273.1    
 cellobiohydrolase (Cel7A) 3.2.1.176 Thielavia australiensis CAD79782.1    
 glycoside hydrolase family 7 protein   Thielavia microspora AGV05127.1    
 endoglucanase 3.2.1.4 Thielavia terrestris CAH03187.1
AAE27824.1
AAE40642.1
AAY00849.1
ABU25926.1
   
 cellobiohydrolase (CBH-II) (Cel6A) 3.2.1.91 Thielavia terrestris ABT06036.1    
 THITE_2110957   Thielavia terrestris NRRL 8126 AEO64667.1    
 cellobiohydrolase (THITE_118360) (Cel7A) 3.2.1.176 Thielavia terrestris NRRL 8126 AEO67172.1    
 THITE_2119040   Thielavia terrestris NRRL 8126 AEO69044.1    
 THITE_126432   Thielavia terrestris NRRL 8126 AEO62210.1    
 THITE_2107967   Thielavia terrestris NRRL 8126 AEO63100.1    
 THITE_2110055   Thielavia terrestris NRRL 8126 AEO64184.1    
 THITE_2111353   Thielavia terrestris NRRL 8126 AEO64954.1    
 THITE_2112626   Thielavia terrestris NRRL 8126 AEO65532.1    
 THITE_165581   Thielavia terrestris NRRL 8126 AEO67421.1    
 THITE_2116333   Thielavia terrestris NRRL 8126 AEO67457.1    
 THITE_2051196   Thielavia terrestris NRRL 8126 AEO67461.1    
 THITE_2117115   Thielavia terrestris NRRL 8126 AEO67939.1    
 THITE_2170662   Thielavia terrestris NRRL 8126 AEO68023.1    
 xylanase (THITE_2117649) 3.2.1.8 Thielavia terrestris NRRL 8126 AEO68222.1    
 THITE_2117885   Thielavia terrestris NRRL 8126 AEO68387.1    
 THITE_123205   Thielavia terrestris NRRL 8126 AEO69910.1    
 THITE_72629   Thielavia terrestris NRRL 8126 AEO70679.1    
 THITE_2122859   Thielavia terrestris NRRL 8126 AEO70954.1    
 THITE_2124663   Thielavia terrestris NRRL 8126 AEO71823.1    
 THITE_2042795   Thielavia terrestris NRRL 8126 AEO63760.1    
 THITE_35493   Thielavia terrestris NRRL 8126 AEO66455.1    
 THITE_2142696   Thielavia terrestris NRRL 8126 AEO67395.1    
 THITE_2117076   Thielavia terrestris NRRL 8126 AEO67907.1    
 THITE_76240   Thielavia terrestris NRRL 8126 AEO68367.1    
 cellobiose dehydrogenase (CbdA,THITE_59724) 1.1.99.18 Thielavia terrestris NRRL 8126 AEO69014.1    
 cellulase-enhancing factor (GH61B)   Thielavia terrestris NRRL 8126 ACE10231.1    
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