Carbohydrate-Binding Module Family 18

Activities in FamilyModules of approx. 40 residues. The chitin-binding function has been demonstrated in many cases. These modules are found attached to a number of chitinase catalytic domains, but also in non-catalytic proteins either in isolation or as multiple repeats.
External resourcesHOMSTRAD; SMART;
Statistics GenBank accession (1633); Uniprot accession (515); PDB accession (38); 3D entries (26); cryst (0)
All (1281) Bacteria (2) Eukaryota (1275) unclassified (4) Structure (26) Characterized (124)
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Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 unnamed protein product   Fusarium graminearum PH-1 CEF86291.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF86291.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF88836.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF88836.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF85876.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF79702.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF79702.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF79702.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF86739.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF86739.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF86739.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF86075.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF86075.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF79102.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF79102.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF79102.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF74633.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF76010.1    
 ORF   Fusarium proliferatum LF061 AEN14642.1    
 ORF   Fusarium proliferatum LF061 AEN14642.1    
 Go-cht1b2   Galega orientalis AAP03089.1 Q7X9F4  
 Go-cht1a   Galega orientalis AAP03088.1 Q7X9F5  
 cht1b   Galega orientalis AAP03087.1 Q7X9F6  
 chtIV   Galega orientalis AAP03085.1 Q7X9F8  
 PR-4 like protein   Galega orientalis AAX51197.1 Q58HA4  
 JCVI-FLGm-5I2   Glycine max ACU14858.1 C6T035  
 unknown   Glycine max ACU17801.1 C6T7J9  
 unknown   Glycine max ACU23323.1 C6TK83  
 chitinase (ChiA1;ChN1) 3.2.1.14 Glycine max AAK01734.1
AAF17593.1
Q9SDY6  
 class IV chitinase   Gossypium barbadense AER29902.1    
 chitinase 3.2.1.14 Gossypium hirsutum AAD11255.1 Q9ZTT8  
 chitinase 1 3.2.1.14 Gossypium hirsutum AAB67842.1
ADI56257.1
D7RTU7
Q39799
 
 chitinase 2 3.2.1.14 Gossypium hirsutum AAB68047.1 Q39785  
 chitinase (fragment)   Halimolobos perplexus var. perplexus AAF69782.1 Q9M7G5  
 hevein (major) (Hev1)   Hevea brasiliensis AAA33357.1
AAG16225.2
AAO63574.1
AAP01387.1
AAQ68982.1
ACP58748.1
P02877 1HEV[A]
1Q9B[A]
1T0W[A]
 hevein (minor)   Hevea brasiliensis   P80359  
 hevein HEV1.1   Hevea brasiliensis AAO63571.1 Q6JYR0  
 hevein HEV1.2   Hevea brasiliensis AAO63572.1 Q6JYQ9  
 hevein (HEV2.1;Hev b 6.02)   Hevea brasiliensis AAO63573.1
ABW34946.1
CAA05978.1
Q6JYQ8 1Q9B[A]
4WP4[A]
 pseudo-hevein (partial)   Hevea brasiliensis CAB62537.1 Q6KF83  
 chitinase-like protein 2 (Clp2;HbCLP2;Chi-L2;LaCIC;Hev b 11.0102)   Hevea brasiliensis AHF88837.1
CAD24068.1
   
 chitinase-like protein 1 / allergen (Rq30;Clp1;Chi-L1;HbCLP1;Hev b 11.0101)   Hevea brasiliensis AHF88836.1
CAC42881.1
Q949H3 4MPI[A,B]
 class 1 chitinase   Hippophae rhamnoides ADP68560.1 E5FQ61  
 class I chitinase (Chi1;HrChi1)   Hippophae rhamnoides AFC88126.1    
 chitinase (Chi-8)   Hirsutella thompsonii MTCC3556 AIT18909.1    
 chitinase (Chi-8)   Hirsutella thompsonii MTCC3556 AIT18909.1    
 chitinase (Chi-12)   Hirsutella thompsonii MTCC3556 AIT18913.1    
 chitinase (Chi-8)   Hirsutella thompsonii MTCC6686 AIT18895.1    
 chitinase (Chi-8)   Hirsutella thompsonii MTCC6686 AIT18895.1    
 chitinase (Chi-12)   Hirsutella thompsonii MTCC6686 AIT18899.1    
 chitinase (Chi-12)   Hirsutella thompsonii MTCC6686 AIT18899.1    
 chitinase 3.2.1.14 Hordeum vulgare AAA18586.1 P11955  
 chitinase-33 (Chi33) 3.2.1.14 Hordeum vulgare AAA56787.1
BAK04967.1
Q42839  
 root-specific lectin   Hordeum vulgare AAA32969.1 P15312  
 root-specific lectin   Hordeum vulgare AAA32969.1 P15312  
 root-specific lectin   Hordeum vulgare AAA32969.1 P15312  
 root-specific lectin   Hordeum vulgare AAA32969.1 P15312  
 NIASHv2116M17   Hordeum vulgare subsp. vulgare BAK01982.1    
 predicted protein (fragment)   Hordeum vulgare subsp. vulgare BAK07956.1    
 predicted protein   Hordeum vulgare subsp. vulgare BAK08163.1    
 chitinase (HCH1) 3.2.1.14 Humulus lupulus AAD34596.1 Q9XFK6  
 chitinase 12   Hypocrella siamensis MTCC 10142 ALI93561.1
ANH56415.1
   
 chitinase 12   Hypocrella siamensis MTCC 10142 ALI93561.1
ANH56415.1
   
 chitinase 14   Hypocrella siamensis MTCC 10142 ALI93563.1
ANH56471.1
   
 chitinase 13   Hypocrella siamensis MTCC 10142 ALI93562.1
ANH56470.1
   
 ORF   Hypocrella siamensis MTCC 10142 ANH56515.1    
 antifungal chitin-binding protein (Afp2;Pn-Afp2;Pn-AMP;PN-AMP1;PN-AMP2)   Ipomoea nil AAA98238.1
AAB18152.1
P81591
Q40095
 
 antifungal chitin-binding protein (Afp1)   Ipomoea nil AAA98236.1
AAA98237.1
Q42468  
 ItChiB (fragment)   Isatis tinctoria ACI23385.1 C3S7U7  
 KAFR_0E00500 (Kafr0e00500)   Kazachstania africana CBS 2517 CCF58204.1    
 KAFR_0L01380 (Kafr0l01380)   Kazachstania africana CBS 2517 CCF60747.1    
 KNAG_0G00480 (Knag0g00480)   Kazachstania naganishii CBS 8797 type strain:CBS 8797 CCK71105.1    
 KNAG_0B02730 (Knag0b02730)   Kazachstania naganishii CBS 8797 type strain:CBS 8797 CCK68716.1    
 chitinase / tRNase killer gammα-toxin (zymocin α-subunit) 3.2.1.14 Kluyveromyces lactis CAA25334.1
CAA25569.1
CAA30137.1
P09805  
 KLLA0F04906g   Kluyveromyces lactis NRRL Y-1140 CAG98010.1 Q6CL87  
 KLLA0F16907g   Kluyveromyces lactis NRRL Y-1140 CAG98547.1 Q6CJQ0  
 KLMA_30283   Kluyveromyces marxianus DMKU3-1042 BAO39578.1    
 KLMA_60522   Kluyveromyces marxianus DMKU3-1042 BAO41813.1    
 KMAR_60510   Kluyveromyces marxianus NBRC 1777 BAP73249.1    
 KMAR_30262   Kluyveromyces marxianus NBRC 1777 BAP71067.1    
 ATY40_BA7501243 (Utr2)   Komagataella pastoris ATCC 28485 ANZ74747.1    
 PP7435_Chr1-0612   Komagataella phaffii CBS 7435 CCA36761.1    
 PAS_chr1-1_0293 (GCW6)   Komagataella phaffii GS115 CAY67669.1
AOA66763.1
C4QWP6  
 AT249_GQ6702877 (Utr2)   Komagataella phaffii WT AOA60885.1    
 KLTH0C03344g   Lachancea thermotolerans CBS 6340 CAR21933.1    
 KLTH0H01914g   Lachancea thermotolerans CBS 6340 CAR30100.1    
 chitinase   Lactuca sativa ACX94236.1 D0QU15  
 functional polypeptide   Lasiodiplodia theobromae CBS 247.96 CAJ81220.1    
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX91375.1 E4ZJU0  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX96933.1 E5A073  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX96933.1 E5A073  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX99804.1 E5A859  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX99804.1 E5A859  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX99804.1 E5A859  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBY02146.1 E5ACE4  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX91631.1 E4ZK36  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX92325.1 E4ZLG6  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX92325.1 E4ZLG6  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX92325.1 E4ZLG6  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX92979.1 E4ZNC0  
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