Carbohydrate-Binding Module Family 13

Activities in FamilyModules of approx. 150 residues which always appear as a threefold internal repeat. The only apparent exception to this, xylanase II of Actinomadura sp. FC7 (GenBank U08894), is in fact not completely sequenced. These modules were first identified in several plant lectins such as ricin or agglutinin of Ricinus communis which bind galactose residues. The three-dimensional structure of a plant lectin has been determined and displays a pseudo-threefold symmetry in accord with the observed sequence threefold repeat. These modules have since been found in a number of other proteins of various functions including glycoside hydrolases and glycosyltransferases. While in the plant lectins this module binds mannose, binding to xylan has been demonstrated in the Streptomyces lividans xylanase A and arabinofuranosidase B. Binding to GalNAc has been shown for the corresponding module of GalNAc transferase 4. For the other proteins, the binding specificity of these modules has not been established. The pseudo three-fold symmetry of the CBM13 module has now been confirmed in the 3-D structure of the intact, two-domain, xylanase of Streptomyces olivaceoviridis.
3D Structure Statusβ-trefoil
NotePreviously known as cellulose-binding domain family XIII (CBD XIII).
External resourcesHOMSTRAD;
Statistics GenBank accession (6103); Uniprot accession (901); PDB accession (146); 3D entries (57); cryst (1)
All (5904) Archaea (23) Bacteria (5240) Eukaryota (598) Viruses (30) unclassified (13) Structure (57 - 1 cryst) Characterized (99)
| 1 | ... | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | ... | 53 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 SAMN05428941_6034   Streptomyces sp. 2114.2 SDT77223.1    
 SAMN05428941_0843   Streptomyces sp. 2114.2 SDS63001.1    
 SAMN05428941_7163   Streptomyces sp. 2114.2 SDT80799.1    
 SAMN05428941_0820   Streptomyces sp. 2114.2 SDS61717.1    
 SAMN05428941_7728   Streptomyces sp. 2114.2 SDT82130.1    
 SAMN05428941_6033   Streptomyces sp. 2114.2 SDT77220.1    
 SAMN05428941_7356   Streptomyces sp. 2114.2 SDT81423.1    
 SAMN06272775_7154   Streptomyces sp. 2323.1 SOE16240.1    
 SAMN06272775_3681   Streptomyces sp. 2323.1 SOE12696.1    
 SAMN06272775_0120   Streptomyces sp. 2323.1 SOE09041.1    
 SAMN06272775_0121   Streptomyces sp. 2323.1 SOE09042.1    
 SAMN05444521_0516   Streptomyces sp. 3214.6 SHH43508.1    
 SAMN05444521_0734   Streptomyces sp. 3214.6 SHH50113.1    
 SAMN05444521_2053   Streptomyces sp. 3214.6 SHH81698.1    
 SAMN05444521_0821   Streptomyces sp. 3214.6 SHH52662.1    
 SAMN05444521_0934   Streptomyces sp. 3214.6 SHH56056.1    
 SAMN05444521_0960   Streptomyces sp. 3214.6 SHH56808.1    
 SAMN05444521_0463   Streptomyces sp. 3214.6 SHH42038.1    
 SAMN05444521_0857   Streptomyces sp. 3214.6 SHH53771.1    
 SAMN05444521_0545   Streptomyces sp. 3214.6 SHH44468.1    
 SAMN05444521_0968   Streptomyces sp. 3214.6 SHH57055.1    
 SAMN05444521_1629   Streptomyces sp. 3214.6 SHH72964.1    
 SAMN05444521_4252   Streptomyces sp. 3214.6 SHI12931.1    
 SAMN05444521_7959   Streptomyces sp. 3214.6 SHI58533.1    
 SAMN05444521_7947   Streptomyces sp. 3214.6 SHI58090.1    
 SAMN05444521_7949   Streptomyces sp. 3214.6 SHI58161.1    
 SAMN05444521_4284   Streptomyces sp. 3214.6 SHI13200.1    
 SAMN05444521_7953   Streptomyces sp. 3214.6 SHI58305.1    
 SAMN05444521_3437   Streptomyces sp. 3214.6 SHI04029.1    
 SAMN05444521_4279   Streptomyces sp. 3214.6 SHI13159.1    
 SAMN05444521_7950   Streptomyces sp. 3214.6 SHI58199.1    
 SAMN05444521_7957   Streptomyces sp. 3214.6 SHI58456.1    
 SAMN05444521_4348   Streptomyces sp. 3214.6 SHI13787.1    
 SAMN05444521_7951   Streptomyces sp. 3214.6 SHI58235.1    
 SAMN05444521_7954   Streptomyces sp. 3214.6 SHI58342.1    
 SAMN05444521_7544   Streptomyces sp. 3214.6 SHI44562.1    
 SAMN05444521_7955   Streptomyces sp. 3214.6 SHI58388.1    
 SAMN05444521_7948   Streptomyces sp. 3214.6 SHI58123.1    
 SAMN05444521_7529   Streptomyces sp. 3214.6 SHI44042.1    
 SAMN05444521_5764   Streptomyces sp. 3214.6 SHI22903.1    
 SAMN05444521_7545   Streptomyces sp. 3214.6 SHI44596.1    
 SAMN05444521_7958   Streptomyces sp. 3214.6 SHI58493.1    
 SAMN05444521_2485   Streptomyces sp. 3214.6 SHH89993.1    
 SAMN05444521_7952   Streptomyces sp. 3214.6 SHI58261.1    
 DC008_29835   Streptomyces sp. 452 AWE53473.1    
 DC008_32575   Streptomyces sp. 452 AWE53953.1    
 DC008_34535   Streptomyces sp. 452 AWE54285.1    
 DC008_33670   Streptomyces sp. 452 AWE54144.1    
 DC008_30355   Streptomyces sp. 452 AWE53562.1    
 DC008_31360   Streptomyces sp. 452 AWE53738.1    
 DC008_33665   Streptomyces sp. 452 AWE54143.1    
 DC008_33400   Streptomyces sp. 452 AWE54095.1    
 DC008_31470   Streptomyces sp. 452 AWE53757.1    
 DC008_13845   Streptomyces sp. 452 AWE50694.1    
 DC008_33310   Streptomyces sp. 452 AWE54079.1    
 DC008_29830   Streptomyces sp. 452 AWE53472.1    
 DC008_33395   Streptomyces sp. 452 AWE54094.1    
 DC008_31445   Streptomyces sp. 452 AWE53752.1    
 DC008_24295   Streptomyces sp. 452 AWE52508.1    
 DC008_30350   Streptomyces sp. 452 AWE53561.1    
 ASR50_33365   Streptomyces sp. 4F ALV53827.1    
 ASR50_31465   Streptomyces sp. 4F ALV53486.1    
 ASR50_01690   Streptomyces sp. 4F ALV48257.1    
 ASR50_15700   Streptomyces sp. 4F ALV50716.1    
 ASR50_01705   Streptomyces sp. 4F ALV48259.1    
 ASR50_02895   Streptomyces sp. 4F ALV48454.1    
 ASR50_32180   Streptomyces sp. 4F ALV53616.1    
 ASR50_03630   Streptomyces sp. 4F ALV48569.1    
 ASR50_31470   Streptomyces sp. 4F ALV53487.1    
 ASR50_07540 (fragment)   Streptomyces sp. 4F ALV49267.1    
 GZL_06227   Streptomyces sp. 769 AJC58797.1    
 GZL_07537   Streptomyces sp. 769 AJC60087.1    
 GZL_08730   Streptomyces sp. 769 AJC61253.1    
 GZL_04824   Streptomyces sp. 769 AJC57402.1    
 GZL_06228   Streptomyces sp. 769 AJC58798.1    
 T261_4367   Streptomyces sp. A02 AJT66020.1    
 T261_8482   Streptomyces sp. A02 AJT70075.1    
 C2142_36405   Streptomyces sp. CB01881 AUY53461.1    
 C2142_28750 (fragment)   Streptomyces sp. CB01881 AUY52257.1    
 C2142_30610   Streptomyces sp. CB01881 AUY52547.1    
 C2142_14235   Streptomyces sp. CB01881 AUY49888.1    
 C2142_28745 (fragment)   Streptomyces sp. CB01881 AUY54544.1    
 C2142_30630   Streptomyces sp. CB01881 AUY54606.1    
 C2142_36465   Streptomyces sp. CB01881 AUY53470.1    
 C2142_00690   Streptomyces sp. CB01881 AUY47728.1    
 C2142_34960   Streptomyces sp. CB01881 AUY53247.1    
 C2142_19040   Streptomyces sp. CB01881 AUY54311.1    
 C2142_36860   Streptomyces sp. CB01881 AUY53521.1    
 C2142_36855   Streptomyces sp. CB01881 AUY53520.1    
 C2142_36620   Streptomyces sp. CB01881 AUY53492.1    
 C2142_02455   Streptomyces sp. CB01881 AUY53904.1    
 C2142_17915   Streptomyces sp. CB01881 AUY50505.1    
 C2142_28740   Streptomyces sp. CB01881 AUY52256.1    
 C2142_28735   Streptomyces sp. CB01881 AUY52255.1    
 C2142_19045   Streptomyces sp. CB01881 AUY50695.1    
 C2142_36625   Streptomyces sp. CB01881 AUY53493.1    
 C2142_09560   Streptomyces sp. CB01881 AUY49140.1    
 NI25_02480   Streptomyces sp. CCM_MD2014 AIV32530.1    
 NI25_09700   Streptomyces sp. CCM_MD2014 AIV33731.1    
 NI25_33880   Streptomyces sp. CCM_MD2014 AIV37899.1    
Top


Last update: 2018-07-09 © Copyright 1998-2018
AFMB - CNRS - Université d'Aix-Marseille