Auxiliary Activity Family 9

Activities in FamilyAA9 (formerly GH61) proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs); cleavage of cellulose chains with oxidation of various carbons (C-1, C-4 and C-6) has been reported several times in the literature;
Mechanism monooxygenase
NoteAA9 (formerly GH61). The enzymes in this family were originally classified as a glycoside hydrolases (GH61) based on very weak endo-1,4-b-D-glucanase activity in one family member. They are now reclassified in the AA category of CAZy. Because a significant literature is associated with the old name GH61, we recommend to describe these enzymes as "AA9 (formerly GH61)".
External resourcesCAZypedia;
Statistics GenBank accession (486); Uniprot accession (135); PDB accession (36); 3D entries (15); cryst (0)
All (406) Eukaryota (406) Structure (15) Characterized (27)
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Protein Name EC#OrganismGenBank UniprotPDB/3D
 PIIN_03975   Serendipita indica DSM 11827 CCA70035.1    
 PIIN_04357   Serendipita indica DSM 11827 CCA70418.1    
 PIIN_04637   Serendipita indica DSM 11827 CCA70703.1    
 PIIN_06117   Serendipita indica DSM 11827 CCA72182.1    
 PIIN_06118   Serendipita indica DSM 11827 CCA72183.1    
 PIIN_06127   Serendipita indica DSM 11827 CCA72192.1    
 PIIN_06155   Serendipita indica DSM 11827 CCA72220.1    
 PIIN_07098   Serendipita indica DSM 11827 CCA73144.1    
 PIIN_07105   Serendipita indica DSM 11827 CCA73151.1    
 PIIN_08199   Serendipita indica DSM 11827 CCA74246.1    
 PIIN_08783   Serendipita indica DSM 11827 CCA74814.1    
 PIIN_09022   Serendipita indica DSM 11827 CCA75037.1    
 PIIN_00566 (fragment)   Serendipita indica DSM 11827 CCA66803.1    
 PIIN_01484   Serendipita indica DSM 11827 CCA67656.1    
 PIIN_01485 (fragment)   Serendipita indica DSM 11827 CCA67657.1    
 PIIN_01486 (fragment)   Serendipita indica DSM 11827 CCA67658.1    
 PIIN_04356   Serendipita indica DSM 11827 CCA70417.1    
 PIIN_05699 (fragment)   Serendipita indica DSM 11827 CCA71764.1    
 PIIN_06156   Serendipita indica DSM 11827 CCA72221.1    
 PIIN_08402   Serendipita indica DSM 11827 CCA74449.1    
 PIIN_10315 (fragment)   Serendipita indica DSM 11827 CCA76320.1    
 PIIN_10660 (fragment)   Serendipita indica DSM 11827 CCA76671.1    
 PIIN_00523 (fragment)   Serendipita indica DSM 11827 CCA77877.1    
 SMU2916 (fragment)   Sordaria macrospora k-hell CAQ58424.1 C1KU36  
 auxiliary activity 9 enzyme   Talaromyces piceae ATQ35955.1    
 lytic polysaccharide mono-oxygenase active on cellulose (TaAA9;TaAA9A;TaGH61;TaGH61A;TaLPMO9A) 1.-.-.- Thermoascus aurantiacus ACS05720.1
 copper-dependent polysaccharide monooxygenases (Gh61) (fragment)   Thermoascus aurantiacus CBS 891.70 CCP37673.1    
 ORF   Thermoascus aurantiacus var. levisporus AGO68294.1    
 copper-dependent polysaccharide monooxygenases (Gh61) (fragment)   Thermomyces dupontii CBS 236.58 CCP37672.1    
 copper-dependent polysaccharide monooxygenases (Gh61) (fragment)   Thermomyces lanuginosus CBS 632.91 CCP37678.1    
 LPMO9B, MtLPMO9B   Thermothelomyces thermophila AON76800.1    
 LPMO9C, MtLPMO9C   Thermothelomyces thermophila AON76801.1    
 MYCTH_2112799   Thermothelomyces thermophila ATCC 42464 AEO61257.1    
 MYCTH_79765   Thermothelomyces thermophila ATCC 42464 AEO56016.1    
 MYCTH_110651   Thermothelomyces thermophila ATCC 42464 AEO54509.1    
 MYCTH_2298502   Thermothelomyces thermophila ATCC 42464 AEO55082.1    
 MYCTH_2299721   Thermothelomyces thermophila ATCC 42464 AEO55652.1    
 MYCTH_2054500   Thermothelomyces thermophila ATCC 42464 AEO55776.1    
 MYCTH_111088   Thermothelomyces thermophila ATCC 42464 AEO56416.1    
 β-glycan-cleaving enzyme (StCel61a;MYCTH_46583) (Cel61A)   Thermothelomyces thermophila ATCC 42464 AEO56542.1 G2Q9T3  
 MYCTH_2301632   Thermothelomyces thermophila ATCC 42464 AEO56547.1    
 MYCTH_100518   Thermothelomyces thermophila ATCC 42464 AEO56642.1    
 lytic polysaccharide monooxygenases (active on cellulose) (MtPMO3;MYCTH_92668) 1.-.-.- Thermothelomyces thermophila ATCC 42464 AEO56665.1   5UFV[A,B,C,D,E,F]
 MYCTH_2060403   Thermothelomyces thermophila ATCC 42464 AEO58412.1    
 MYCTH_2306673   Thermothelomyces thermophila ATCC 42464 AEO58921.1    
 MYCTH_116175 (fragment)   Thermothelomyces thermophila ATCC 42464 AEO59482.1    
 MYCTH_96032   Thermothelomyces thermophila ATCC 42464 AEO59823.1    
 MYCTH_103537   Thermothelomyces thermophila ATCC 42464 AEO59836.1    
 MYCTH_55803   Thermothelomyces thermophila ATCC 42464 AEO59955.1    
 lytic polysaccharide monooxygenases (active on cellulose) (MYCTH_112089;MYCTH112089) 1.-.-.- Thermothelomyces thermophila ATCC 42464 AEO60271.1    
 MYCTH_85556   Thermothelomyces thermophila ATCC 42464 AEO61304.1    
 MYCTH_2311323   Thermothelomyces thermophila ATCC 42464 AEO61305.1    
 MYCTH_47093 (fragment)   Thermothelomyces thermophila ATCC 42464 AEO56498.1    
 MYCTH_80312   Thermothelomyces thermophila ATCC 42464 AEO58169.1    
 lytic polysaccharide monooxygenase active on cellulose and xylan (MtLPMO9A) (LPMO9A) 1.-.-.- Thermothelomyces thermophila C1 AKO82493.1    
 LPMO9D   Thermothelomyces thermophila C1 ASE05899.1    
 unnamed protein product   Thielavia terrestris CAG27576.1    
 THITE_2106556   Thielavia terrestris NRRL 8126 AEO62422.1    
 THITE_2116536   Thielavia terrestris NRRL 8126 AEO67662.1    
 THITE_2040127   Thielavia terrestris NRRL 8126 AEO64605.1    
 THITE_2119040   Thielavia terrestris NRRL 8126 AEO69044.1    
 THITE_115795   Thielavia terrestris NRRL 8126 AEO64177.1    
 THITE_2110890   Thielavia terrestris NRRL 8126 AEO64593.1    
 THITE_2112626   Thielavia terrestris NRRL 8126 AEO65532.1    
 THITE_2076863   Thielavia terrestris NRRL 8126 AEO65580.1    
 THITE_170174   Thielavia terrestris NRRL 8126 AEO66274.1    
 THITE_2044372   Thielavia terrestris NRRL 8126 AEO67396.1    
 THITE_2170662   Thielavia terrestris NRRL 8126 AEO68023.1    
 THITE_128130   Thielavia terrestris NRRL 8126 AEO68157.1    
 THITE_2145386   Thielavia terrestris NRRL 8126 AEO68577.1    
 THITE_2054543   Thielavia terrestris NRRL 8126 AEO68763.1    
 THITE_2059487   Thielavia terrestris NRRL 8126 AEO71031.1    
 THITE_2142696   Thielavia terrestris NRRL 8126 AEO67395.1    
 THITE_43665   Thielavia terrestris NRRL 8126 AEO69043.1    
 THITE_2085430 (fragment)   Thielavia terrestris NRRL 8126 AEO63926.1    
 THITE_2122979   Thielavia terrestris NRRL 8126 XP_003657366.1
 cellulase-enhancing factor (GH61B)   Thielavia terrestris NRRL 8126 ACE10231.1    
 Sequence 4 from patent US 7361495 (GH61C)   Thielavia terrestris NRRL 8126 ACE10232.1    
 Sequence 4 from patent US 7361495 (GH61C)   Thielavia terrestris NRRL 8126 ACE10232.1    
 Sequence 6 from patent US 7361495 (GH61D)   Thielavia terrestris NRRL 8126 ACE10233.1    
 Sequence 6 from patent US 7361495 (GH61D)   Thielavia terrestris NRRL 8126 ACE10233.1    
 Sequence 10 from patent US 7361495 (GH61G)   Thielavia terrestris NRRL 8126 ACE10235.1    
 Sequence 10 from patent US 7361495 (GH61G)   Thielavia terrestris NRRL 8126 ACE10235.1    
 lytic polysaccharide mono-oxygenase active on cellulose (EG7;HjGH61B) (Cel61B=GH61B)   Trichoderma reesei QM6A AAP57753.1
Q7Z9M7 2VTC[A,B]
 lytic cellulose monooxygenase (EGIV;Egl4;EG4) (formerly endo-β-1,4-glucanase IV) (LPMO9A) 1.-.-.- Trichoderma reesei RUTC-30 CAA71999.1 O14405 5O2W[A]
 endoglucanase (EnGluIV;EndoGluIV)   Trichoderma saturnisporum ADB89217.1 D3JTC4  
 endoglucanase IV (EgIV;EG IV)   Trichoderma sp. SSL ACH92573.1 B5TYI4  
 endo-1,4-D-glucanase, partial   Trichoderma virens ARQ82881.1    
 endoglucanase VII (EgvII)   Trichoderma viride AS 3.3711 ACD36971.1 B4YEW1  
 endoglucanase IV (EgIV)   Trichoderma viride AS 3.3711 ADJ57703.1
 AAA12YM05FL   uncultured eukaryote CCA94933.1    
 AAA2YG01FL   uncultured eukaryote CCA94930.1    
 AAA15YI10FL   uncultured eukaryote CCA94931.1    
 AAA21YH11FL   uncultured eukaryote CCA94932.1    
 ABA3YP05FL   uncultured eukaryote CCA94934.1    
 endoglucanase II (EgII)   Volvariella volvacea AFP23133.1    
 copper-dependent lytic polysaccharide monooxygenase   Volvariella volvacea PYd21 AKR15724.1    
 endoglucanase II (EgII)   Volvariella volvacea V14 AAT64005.1 Q6E5B4  
 ZT1A5_G3397   Zymoseptoria tritici ST99CH_1A5 SMY21959.1    
 ZT1A5_G1434   Zymoseptoria tritici ST99CH_1A5 SMY19999.1    

Last update: 2018-08-08 © Copyright 1998-2018
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