Auxiliary Activity Family 9

Activities in FamilyAA9 (formerly GH61) proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs); cleavage of cellulose chains with oxidation of various carbons (C-1, C-4 and C-6) has been reported several times in the literature;
Mechanism monooxygenase
NoteAA9 (formerly GH61). The enzymes in this family were originally classified as a glycoside hydrolases (GH61) based on very weak endo-1,4-b-D-glucanase activity in one family member. They are now reclassified in the AA category of CAZy. Because a significant literature is associated with the old name GH61, we recommend to describe these enzymes as "AA9 (formerly GH61)".
External resourcesCAZypedia;
Statistics GenBank accession (432); Uniprot accession (135); PDB accession (26); 3D entries (12); cryst (0)
All (352) Eukaryota (352) Structure (12) Characterized (26)
| 1 | 2 | 3 | 4 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 MYCTH_85556   Thermothelomyces thermophila ATCC 42464 AEO61304.1    
 MYCTH_2311323   Thermothelomyces thermophila ATCC 42464 AEO61305.1    
 MYCTH_47093 (fragment)   Thermothelomyces thermophila ATCC 42464 AEO56498.1    
 MYCTH_80312   Thermothelomyces thermophila ATCC 42464 AEO58169.1    
 lytic polysaccharide monooxygenase active on cellulose and xylan (MtLPMO9A) (LPMO9A) 1.-.-.- Thermothelomyces thermophila C1 AKO82493.1    
 LPMO9D   Thermothelomyces thermophila C1 ASE05899.1    
 unnamed protein product   Thielavia terrestris CAG27576.1    
 THITE_2106556   Thielavia terrestris NRRL 8126 AEO62422.1    
 THITE_2116536   Thielavia terrestris NRRL 8126 AEO67662.1    
 THITE_2040127   Thielavia terrestris NRRL 8126 AEO64605.1    
 THITE_2119040   Thielavia terrestris NRRL 8126 AEO69044.1    
 THITE_115795   Thielavia terrestris NRRL 8126 AEO64177.1    
 THITE_2110890   Thielavia terrestris NRRL 8126 AEO64593.1    
 THITE_2112626   Thielavia terrestris NRRL 8126 AEO65532.1    
 THITE_2076863   Thielavia terrestris NRRL 8126 AEO65580.1    
 THITE_170174   Thielavia terrestris NRRL 8126 AEO66274.1    
 THITE_2044372   Thielavia terrestris NRRL 8126 AEO67396.1    
 THITE_2170662   Thielavia terrestris NRRL 8126 AEO68023.1    
 THITE_128130   Thielavia terrestris NRRL 8126 AEO68157.1    
 THITE_2145386   Thielavia terrestris NRRL 8126 AEO68577.1    
 THITE_2054543   Thielavia terrestris NRRL 8126 AEO68763.1    
 THITE_2059487   Thielavia terrestris NRRL 8126 AEO71031.1    
 THITE_2142696   Thielavia terrestris NRRL 8126 AEO67395.1    
 THITE_43665   Thielavia terrestris NRRL 8126 AEO69043.1    
 THITE_2085430 (fragment)   Thielavia terrestris NRRL 8126 AEO63926.1    
 THITE_2122979   Thielavia terrestris NRRL 8126 XP_003657366.1
ACE10234.1
AEO71030.1
  3EII[A,B,C,D]
3EJA[A,B,C,D]
 cellulase-enhancing factor (GH61B)   Thielavia terrestris NRRL 8126 ACE10231.1    
 Sequence 4 from patent US 7361495 (GH61C)   Thielavia terrestris NRRL 8126 ACE10232.1    
 Sequence 4 from patent US 7361495 (GH61C)   Thielavia terrestris NRRL 8126 ACE10232.1    
 Sequence 6 from patent US 7361495 (GH61D)   Thielavia terrestris NRRL 8126 ACE10233.1    
 Sequence 6 from patent US 7361495 (GH61D)   Thielavia terrestris NRRL 8126 ACE10233.1    
 Sequence 10 from patent US 7361495 (GH61G)   Thielavia terrestris NRRL 8126 ACE10235.1    
 Sequence 10 from patent US 7361495 (GH61G)   Thielavia terrestris NRRL 8126 ACE10235.1    
 lytic polysaccharide mono-oxygenase active on cellulose (EG7;HjGH61B) (Cel61B=GH61B)   Trichoderma reesei QM6A AAP57753.1
ABH82048.1
ACK19226.1
ACR92640.1
Q7Z9M7 2VTC[A,B]
 lytic cellulose monooxygenase (EGIV;Egl4;EG4) (formerly endo-β-1,4-glucanase IV) (LPMO9A) 1.-.-.- Trichoderma reesei RUTC-30 CAA71999.1 O14405 5O2W[A]
5O2X[A]
 endoglucanase (EnGluIV;EndoGluIV)   Trichoderma saturnisporum ADB89217.1 D3JTC4  
 endoglucanase IV (EgIV;EG IV)   Trichoderma sp. SSL ACH92573.1 B5TYI4  
 endo-1,4-D-glucanase, partial   Trichoderma virens ARQ82881.1    
 endoglucanase VII (EgvII)   Trichoderma viride AS 3.3711 ACD36971.1 B4YEW1  
 endoglucanase IV (EgIV)   Trichoderma viride AS 3.3711 ADJ57703.1
ACD36973.1
B4YEW3
D9IXC6
 
 AAA12YM05FL   uncultured eukaryote CCA94933.1    
 AAA2YG01FL   uncultured eukaryote CCA94930.1    
 AAA15YI10FL   uncultured eukaryote CCA94931.1    
 AAA21YH11FL   uncultured eukaryote CCA94932.1    
 ABA3YP05FL   uncultured eukaryote CCA94934.1    
 endoglucanase II (EgII)   Volvariella volvacea AFP23133.1    
 copper-dependent lytic polysaccharide monooxygenase   Volvariella volvacea PYd21 AKR15724.1    
 endoglucanase II (EgII)   Volvariella volvacea V14 AAT64005.1 Q6E5B4  
 ZT1A5_G3397   Zymoseptoria tritici ST99CH_1A5 SMY21959.1    
 ZT1A5_G1434   Zymoseptoria tritici ST99CH_1A5 SMY19999.1    
 ZT3D7_G3415   Zymoseptoria tritici ST99CH_3D7 SMQ48266.1    
 ZT3D7_G1459   Zymoseptoria tritici ST99CH_3D7 SMQ46313.1    
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