Auxiliary Activity Family 3

Activities in Familycellobiose dehydrogenase (EC 1.1.99.18); glucose 1-oxidase (EC 1.1.3.4); aryl alcohol oxidase (EC 1.1.3.7); alcohol oxidase (EC 1.1.3.13); pyranose oxidase (EC 1.1.3.10); glucose 1-dehydrogenase (FAD, quinone) (EC 1.1.5.9); pyranose dehydrogenase (EC 1.1.99.29); oligosaccharide dehydrogenase (FAD) (EC 1.1.5.-)
NoteAA3 enzymes belong to the glucose-methanol-choline (GMC) oxidoreductases family. AA3 enzymes are flavoproteins containing a flavin-adenine dinucleotide (FAD)-binding domain. Family AA3 can be divided into 4 subfamilies: AA3_1 (mostly cellobiose dehydrogenases), AA3_2 (including both aryl alcohol oxidase and glucose 1-oxidase), AA3_3 (alcohol oxidase) and AA3_4 (pyranose 2-oxidase).
External resourcesCAZypedia;
Statistics GenBank accession (2567); Uniprot accession (44); PDB accession (54); 3D entries (18); cryst (1)
Eukaryota
Protein Name EC#OrganismGenBankUniprot
PDB/3DResolution (Å)
Subf
 glucose dehydrogenase (GDH,G4B84_001660) 1.1.5.9 Aspergillus flavus NRRL3357 QMW26415.1  
4YNT[A] 1.78
4YNU[A] 1.57
2
 glucose oxidase (Gox1) 1.1.3.4 Aspergillus niger AAA32695.1
AAB12628.1
AAQ78793.1
ACB30369.1
CAA34197.1
CAC27315.1
CAC83816.1
B2CNX8
P13006
1CF3[A] 1.90
1GAL[A] 2.30
3QVP[A] 1.20
3QVR[A] 1.30
5NIT[A] 1.87
5NIW[A] 1.80
2
 5991   Aspergillus oryzae RIB40    
5ZU3[A,B,C] 2.40
2
 cellobiose dehydrogenase IIA (Cdh;MtCDH) 1.1.99.18 Crassicarpon hotsonii ABS45567.2
ABS45566.1
A9XK87
A9XK88
4QI4[A] 2.70
4QI5[A] 2.40
4QI6[A] 3.20
1
 alcohol oxidase / methanol oxidase (Aox1;AOX1;MOX1) 1.1.3.13 Komagataella pastoris NRRL Y-11430 AAB57849.1 F2QY27
P04842
5HSA[A,B,C,D,E,F,G,H] 2.35
5I68[A] 3.37
3
 pyranose dehydrogenase (Pdh1;PDH;AmPDH) 1.1.99.29 Leucoagaricus meleagris AAW82996.1
AAW82997.1
Q3L245
4H7U[A] 1.60
2
 cellobiose dehydrogenase IIA (Cdh-1;CDH-1;CdhIIA;Nc-Cdh1;NCU00206) 1.1.99.18 Neurospora crassa OR74A EAA27355.1
XP_322292.1
Q7RXM0
4QI7[A,B] 2.90
1
 glucose oxidase 1.1.3.4 Penicillium amagasakiense   P81156
1GPE[A,B] 1.80
2
 pyranose 2-oxidase / glucose 2-oxidase 1.1.3.10 Peniophora sp. SG AAO13382.1 Q8J136
1TZL[A,B,C,D,E,F,G,H] 2.35
2F5V[A] 1.41
2F6C[A] 1.84
4
 pyranose 2-oxidase (PoX) 1.1.3.10 Phanerochaete chrysosporium BKM-F-1767 AAS93628.1
Q6QWR1.1
Q6QWR1
4MIF[A,B,C,D] 1.80
4MIG[A,B,C,D] 1.80
4MIH[A,B,C,D,E,F,G,H] 2.40
4
 alcohol oxidase (Aox1) 1.1.3.13 Phanerochaete chrysosporium DSMZ 1547 CDG66232.1 T2M2J4
6H3G[A,B,C,D,E,F,G,H] 2.60
6H3O[A,B,C,D,E,F,G,H] 2.50
3
 cellobiose dehydrogenase (CdH)   Phanerochaete chrysosporium OGC101 AAC49277.1  
1KDG[A,B] 1.50
1NAA[A,B] 1.80
1
 aryl-alcohol oxidase (AaO) 1.1.3.7 Pleurotus eryngii ATCC90787; CBS 613.91; IJFM A169 AAC72747.1 O94219
3FIM[B] 2.55
5OC1[A] 2.30
2
 aryl-alcohol oxidase (AaO) 1.1.3.7 Pleurotus pulmonarius CBS 507.85 AAF31169.1 Q9P928
cryst  
2
 ORF   Thermochaetoides thermophila DSM 1495    
6ZE3[A] 2.22
6ZE4[A] 1.60
6ZE5[A] 1.82
6ZE6[A] 1.26
6ZE7[A] 1.50
7AA2[A] 1.40
6ZE2[A] 1.31
2
 aryl-alcohol oxidase (MYCTH_2299749)   Thermothelomyces thermophilus ATCC 42464 XP_003660923.1  
6O9N[A,B] 2.60
2
 oligosaccharide dehydrogenase (ODH;BN946_scf184803.g17) 1.1.5.- Trametes cinnabarina BRFM137 CDO69819.1  
6XUT[A] 1.60
6XUU[A] 1.57
6XUV[A] 1.75
2
 pyranose 2-oxidase (P2O;TmP2O) 1.1.3.10 Trametes ochracea MB49 AAP40332.1 Q7ZA32
4MOE[A,B,C,D] 2.00
4MOF[A] 1.85
4MOG[A] 2.00
4MOH[A] 2.10
4MOI[A,B] 1.90
4MOJ[A,B,C,D] 2.00
4MOK[A,B,C,D] 1.90
4MOL[A,B,C,D] 2.00
4MOM[A,B,C,D] 1.90
4MOO[A] 1.65
4MOP[A,B,C,D] 2.30
4MOQ[A,B] 1.60
4MOR[A,B,C,D] 1.50
4MOS[A] 1.80
4
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