Auxiliary Activity Family 13

Activities in FamilyAA13 proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs); cleavage of starch with oxidation of C-1 at the site of cleavage has been demonstrated for the LPMO encoded by gene NCU08746 from Neurospora crassa;
Mechanism monooxygenase
NoteFamily built after Vu et al. Proc. Natl. Acad. Sci. USA (2014) 111:13822-7 (PMID 25201969);
Statistics GenBank accession (23); Uniprot accession (8); PDB accession (4); 3D entries (1); cryst (0)
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 EGX44447.1   Arthrobotrys oligospora ATCC 24927 EGX44447.1    
 lytic starch monooxygenase (AnAA13;AN5463.2) 1.-.-.- Aspergillus nidulans FGSC A4 EAA62623.1 C8VGF8
Q5B1W7
 
 AN6103.2   Aspergillus nidulans FGSC A4 EAA58078.1    
 lytic monooxygenase (AoAA13;AO090701000246;AOR_1_454114)   Aspergillus oryzae RIB40 XP_001823115.2
BAE61982.1
Q2U8Y3 4OPB[A]
5LSV[A]
5T7J[A]
5T7N[A]
 lytic starch monooxygenase (AtLPMO13A;ATEG_07286) 1.-.-.- Aspergillus terreus NIH2624 EAU32670.1    
 carbohydrate-Binding Module family 20 protein (Bofut4_p141390.1)   Botrytis cinerea T4 CCD56877.1
CCD56877.2
   
 FFUJ_13991   Fusarium fujikuroi IMI 58289 CCT72014.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF86045.1    
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX99030.1 E5A5Y5  
 MoLPMO13A (MG10208;MGCH7_ch7g978)   Magnaporthe oryzae 70-15 XP_365988.1
EAQ71571.1
Q2KEQ8  
 lytic polysaccharide mono-oxygenase active on starch (NcAA13;NCU08746) 1.-.-.- Neurospora crassa OR74A EAA34371.2
CAE75704.1
EAA34371.1
XP_330863.1
Q7SCE9  
 Pc13g11940   Penicillium rubens Wisconsin 54-1255 CAP92263.1 B6H504  
 PCH_Pc20g13600   Penicillium rubens Wisconsin 54-1255 CAP86689.1    
 Pa_3_10650 (fragment)   Podospora anserina S mat+ CAP61339.1
CDP27694.1
B2AD24  
 sscle_15g105380   Sclerotinia sclerotiorum 1980 UF-70 APA15768.1    
 MYCTH_2313229   Thermothelomyces thermophila ATCC 42464 AEO62162.1    
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