Auxiliary Activity Family 13

Activities in FamilyAA13 proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs); cleavage of starch with oxidation of C-1 at the site of cleavage has been demonstrated for the LPMO encoded by gene NCU08746 from Neurospora crassa; lytic starch monooxygenase / starch oxidase (glycosidic bond-cleaving) (EC 1.14.99.55)
Mechanism monooxygenase
NoteFamily built after Vu et al. Proc. Natl. Acad. Sci. USA (2014) 111:13822-7 (PMID 25201969);
External resourcesCAZypedia;
Statistics GenBank accession (41); Uniprot accession (7); PDB accession (8); 3D entries (1); cryst (0)
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 lytic starch monooxygenase (AnAA13;AN5463.2) 1.14.99.55   Aspergillus nidulans FGSC A4 EAA62623.1 A0A1U8QN05
C8VGF8
Q5B1W7
 
 lytic monooxygenase (AoAA13;AO090701000246;AOR_1_454114) 1.14.99.55   Aspergillus oryzae RIB40 XP_001823115.2
BAE61982.1
Q2U8Y3 4OPB[A]
5LSV[A]
5T7J[A]
5T7K[A]
5T7N[A]
6TBQ[A]
6TBR[A,B]
6TC4[A]
 lytic starch monooxygenase (AtLPMO13A;ATEG_07286) 1.14.99.55   Aspergillus terreus NIH2624 EAU32670.1 Q0CGA6  
 lytic polysaccharide mono-oxygenase active on starch (NcAA13;NCU08746) 1.14.99.55   Neurospora crassa OR74A EAA34371.2
CAE75704.1
EAA34371.1
XP_330863.1
Q6MWQ3
Q7SCE9
 
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