Auxiliary Activity Family 10

Activities in FamilyAA10 (formerly CBM33) proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs); some proteins have been shown to act on chitin, others on cellulose;
Mechanism monooxygenase
NoteAA10 (formerly CBM33). The enzymes in this family were originally classified as chitin-binding proteins (CBM33); Vaaje-Kolstad et al. have shown that these proteins are in fact oxidative enzymes [PMID - 20929773]. They are now reclassified in the AA category of CAZy. Because a significant literature is associated with the old name CBM33, we recommend to describe these enzymes as "AA10 (formerly CBM33)".
Statistics GenBank accession (3211); Uniprot accession (385); PDB accession (33); 3D entries (17); cryst (0)
All (3070) Archaea (2) Bacteria (2918) Eukaryota (7) Viruses (141) unclassified (2) Structure (17) Characterized (19)
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Viruses
Protein Name EC#OrganismGenBank UniprotPDB/3D
 GP37   Lymantria dispar multiple nucleopolyhedrovirus 3029 AIX47907.1    
 GP37   Lymantria dispar multiple nucleopolyhedrovirus 3041 AMO27739.1    
 GP37   Lymantria dispar multiple nucleopolyhedrovirus 3054 AMO27566.1    
 GP37   Lymantria dispar multiple nucleopolyhedrovirus Ab-a624 AMO27922.1    
 GP37 (Gp37)   Lymantria xylina MNPV ADD73773.1 D4N2A1  
 gp37 (Masp1.23)   Malacosoma sp. alphabaculovirus 164 ANW12256.1    
 gp37   Mamestra brassicae multiple nucleopolyhedrovirus AIL25109.1    
 Mb_orf32   Mamestra brassicae multiple nucleopolyhedrovirus CHb1 AFP95751.1    
 MabrNPVgp031 (Gp37)   Mamestra brassicae multiple nucleopolyhedrovirus K1 AFL64882.1    
 Gp37   Mamestra brassicae multiple nucleopolyhedrovirus Oxford AAD45231.1 Q9WR40  
 ORF 37 (Gp37)   Mamestra configurata nucleopolyhedrovirus A AAQ11056.1
AAM09145.1
Q71AH5
Q8QLJ7
 
 Gp37   Mamestra configurata nucleopolyhedrovirus B AAM95019.1
NP_689207.1
Q8JMC0  
 gp37   Maruca vitrata MNPV ABL76000.1 A1YRB0  
 MYSEV_174   Mythimna separata entomopoxvirus L CCU56372.1    
 Gp37   Orgyia leucostigma nucleopolyhedrovirus ABY65755.1 B0FDP7  
 OpmnVgp069 (Gp37;ORF69)   Orgyia pseudotsugata multiple nucleopolyhedrovirus AAC59068.1
BAA02566.1
NP_046225.1
Q65328  
 pesp022   Peridroma alphabaculovirus AIE47753.1    
 ORF   Perigonia lusca single nucleopolyhedrovirus AKN80640.1    
 gp50 spindlin (ORF-83)   Philosamia cynthia ricini nucleopolyhedrovirus virus AFY62890.1    
 PrGVORF13 / Pirα-GV_ORF013 (GP37)   Pieris rapae granulovirus ACZ63499.1
ADO85438.1
AGS18777.1
D2J4I0  
 ORF   Plutella xylostella multiple nucleopolyhedrovirus ABE68450.1 Q0GYF8  
 enhancing factor (EF)   Pseudaletia separata entomopoxvirus BAA09138.1 O12686  
 Gp37 (Orf110)   Pseudaletia unipuncta granulovirus Hawaiin ACH69460.1 B6S6X9  
 37 kDa glycoprotein (Orf-67)   Pseudoplusia includens SNPV IE AJD80757.1    
 ORF25   Spodoptera exigua multiple nucleopolyhedrovirus AAF33555.1
CDG72366.1
CDG72503.1
CDG72640.1
CDG72777.1
CDG72929.1
CDG73066.1
CDG73203.1
NP_037785.1
Q9J8B0  
 glycoprotein GP37   Spodoptera frugiperda multiple nucleopolyhedrovirus AIW01435.1    
 GP37   Spodoptera frugiperda multiple nucleopolyhedrovirus ACA02581.1    
 gp37 (fragment)   Spodoptera frugiperda multiple nucleopolyhedrovirus 3AP2 AAP79107.1 Q6X861  
 gp37   Spodoptera frugiperda multiple nucleopolyhedrovirus 3AP2 ABM45735.1 A1YJ14  
 SlsnVgp028   Spodoptera littoralis nucleopolyhedrovirus AGE89883.1    
 ubiquitin GP37 fusion protein   Spodoptera litura nucleopolyhedrovirus G2 AAL01718.1
NP_258300.1
Q91BI7  
 Gp37 (Orf22)   Spodoptera litura nucleopolyhedrovirus II ACI47391.1 B7SVP9  
 gp37   Sucra jujuba nucleopolyhedrovirus AIU41291.1    
 GP37   Thysanoplusia orichalcea nucleopolyhedrovirus ABV69584.1
AGA16215.1
A8DDD1  
 gp37   Trichoplusia ni granulovirus AOW41440.1    
 Gp37 (Orf64)   Trichoplusia ni single nucleopolyhedrovirus AAZ67435.1 Q462A1  
 fusolin (partial)   unidentified entomopoxvirus     4YN2[A]
 Sequence 11 from patent US 7009090   unidentified entomopoxvirus ABE23213.1    
 Sequence 13 from patent US 7009090   unidentified entomopoxvirus ABE23215.1    
 fusolin   unidentified entomopoxvirus / Melolontha melolontha entomopoxvirus (MMEV) CAA54706.1
ABE23214.1
Q83389 4OW5[A]
4X27[A]
4X29[A]
 XecnGVgp107 (Orf107)   Xestia c-nigrum granulovirus AAF05221.1
ABE23220.1
NP_059255.1
Q9PYT6  
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