Auxiliary Activity Family 10

Activities in FamilyAA10 (formerly CBM33) proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs); some proteins have been shown to act on chitin, others on cellulose; lytic cellulose monooxygenase (C1-hydroxylating) (EC 1.14.99.54); lytic cellulose monooxygenase (C4-dehydrogenating)(EC 1.14.99.56); lytic chitin monooxygenase (EC 1.14.99.53)
Mechanism monooxygenase
NoteAA10 (formerly CBM33). The enzymes in this family were originally classified as chitin-binding proteins (CBM33); Vaaje-Kolstad et al. have shown that these proteins are in fact oxidative enzymes [PMID - 20929773]. They are now reclassified in the AA category of CAZy. Because a significant literature is associated with the old name CBM33, we recommend to describe these enzymes as "AA10 (formerly CBM33)".
Statistics GenBank accession (4887); Uniprot accession (382); PDB accession (35); 3D entries (19); cryst (0)
All (4731) Archaea (3) Bacteria (4549) Eukaryota (9) Viruses (168) unclassified (2) Structure (19) Characterized (22)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 SAMN05216594_2678   Pseudomonas fragi NRRL B-727 SDU45716.1    
 BLL42_02585   Pseudomonas frederiksbergensis ERDD5:01 APC14669.1    
 AL527_03565   Pseudomonas fulva FDAARGOS_167 AVF54323.1    
 KF707C_50340   Pseudomonas furukawaii KF707 BAU76722.1    
 KF707C_50360   Pseudomonas furukawaii KF707 BAU76724.1    
 SAMN05216581_0999   Pseudomonas fuscovaginae LMG 2158 SEH98455.1    
 SAMN05216581_5958   Pseudomonas fuscovaginae LMG 2158 SEI25590.1    
 SAMN05216579_3016   Pseudomonas granadensis LMG 27940 SDT26149.1    
 SAMN04490189_0208   Pseudomonas koreensis BS3658 SDC66209.1    
 A8L59_10425   Pseudomonas koreensis CRS05-R5 ANH97806.1    
 AYO71_19475   Pseudomonas koreensis D26 AMT91445.1    
 PkP19E3_10780   Pseudomonas koreensis P19E3 AVX88789.1    
 DLD99_17825   Pseudomonas kribbensis 46-2 AXI62253.1    
 SAMN04490190_5953   Pseudomonas libanensis BS2975 SDL59576.1    
 OU5_1149 (fragment)   Pseudomonas mandelii JR-1 AHZ68228.1    
 SAMN04489801_6429   Pseudomonas mandelii LMG 21607 SDU71633.1    
 SAMN05216476_0107   Pseudomonas mediterranea DSM 16733 SDU02937.1    
 PSMEN_21435   Pseudomonas mendocina NSYSU ARS50828.1    
 Pmen_4108   Pseudomonas mendocina ymp ABP86855.1 A4XZT9  
 AL532_09280   Pseudomonas monteilii FDAARGOS_171 AVH36488.1    
 SAMN04490196_1071   Pseudomonas moraviensis BS3668 SDU22508.1    
 CLJ08_01850   Pseudomonas mosselii BS011 ATB63433.1    
 O165_007215   Pseudomonas mosselii SJ10 AIN58093.1    
 SAMN05216202_1695   Pseudomonas mucidolens LMG 2223 SDU92404.1    
 NCTC8068_02876   Pseudomonas mucidolens NCTC8068 SQH33892.1    
 CYL20_02700   Pseudomonas palleroniana MAB3 AVE03517.1    
 B2J77_03680   Pseudomonas parafulva PRS09-11288 AQW67395.1    
 DVB73_06010   Pseudomonas plecoglossicida XSDHY-P AXM95390.1    
 EJJ20_04530 (GbpA)   Pseudomonas poae CAP-2018 AZP69861.1    
 EJJ20_09020 (fragment)   Pseudomonas poae CAP-2018 AZP70409.1    
 EJJ20_09025 (fragment)   Pseudomonas poae CAP-2018 AZP70410.1    
 SAMN05216222_0350   Pseudomonas prosekii LMG 26867 SDR94247.1    
 PPC_2103   Pseudomonas protegens Cab57 BAO61450.1    
 PFLCHA0_c21370   Pseudomonas protegens CHA0 AGL83909.1
VAV68418.1
   
 DWF74_04290   Pseudomonas protegens FD6 AXK52607.1    
 DWF74_04275   Pseudomonas protegens FD6 AXK52604.1    
 DWF74_04285   Pseudomonas protegens FD6 AXK52606.1    
 DWF74_04280   Pseudomonas protegens FD6 AXK52605.1    
 DWF74_26285   Pseudomonas protegens FD6 AXK56706.1    
 CEP86_29460   Pseudomonas protegens FDAARGOS_307 ASE24383.1    
 H78_02273   Pseudomonas protegens H78 AQT08947.1    
 H78_04056   Pseudomonas protegens H78 AQT10715.1    
 H78_04057   Pseudomonas protegens H78 AQT10716.1    
 PFL_2090   Pseudomonas protegens Pf-5 AAY91365.1 Q4KEY5  
 AWT69_002084   Pseudomonas putida 1A00316 AMK30721.1    
 AWT69_004336   Pseudomonas putida 1A00316 AMK32973.1    
 CR511_25815   Pseudomonas putida E41 ATP47281.1    
 YSA_04277   Pseudomonas putida ND6 AFK69082.1    
 C1S65_25210   Pseudomonas putida NX-1 AXA27251.1    
 A210_25385   Pseudomonas putida SJTE-1 ANI05849.1    
 PputW619_0797   Pseudomonas putida W619 ACA71302.1 B1J2U9  
 SAMN04490209_5549   Pseudomonas rhodesiae BS2777 SDV16530.1    
 PS417_25165   Pseudomonas simiae WCS417 AIB38807.1    
 PS417_25145 (fragment)   Pseudomonas simiae WCS417 AIB38804.1    
 CXQ81_27560   Pseudomonas sp. 09C 129 AUG04206.1    
 CXQ81_18685   Pseudomonas sp. 09C 129 AUG02551.1    
 CXQ81_12640   Pseudomonas sp. 09C 129 AUG01414.1    
 EPZ47_02100 (GbpA)   Pseudomonas sp. 11K1 QBZ87549.1    
 EPZ47_11530   Pseudomonas sp. 11K1 QBZ89313.1    
 DJ564_12440   Pseudomonas sp. 31-12 AWM91576.1    
 SAMN05216509_1105   Pseudomonas sp. B10 SIR21733.1    
 AA042_12025   Pseudomonas sp. BS-2016 AU1044 AOZ13299.1    
 SAMN04490210_2079   Pseudomonas sp. bs2935 SDS29227.1    
 SAMN04490210_0632   Pseudomonas sp. bs2935 SDR84185.1    
 CCOS191_3053   Pseudomonas sp. CCOS 191 CRI57589.1    
 C4K39_2137   Pseudomonas sp. CMR12a AZC23812.1    
 C4K40_2127   Pseudomonas sp. CMR5c AZC17517.1    
 PDR5_36300   Pseudomonas sp. DR 5-09 ANI55360.1    
 BL240_26595   Pseudomonas sp. DRA525 APO85524.1    
 C2E19_18390   Pseudomonas sp. DTU12.3 QAX85693.1    
 CRN80_19090   Pseudomonas sp. FDAARGOS_380 ATN11624.1    
 C4J83_4251   Pseudomonas sp. LBUM920 AZF65223.1    
 C4J83_2664   Pseudomonas sp. LBUM920 AZF63653.1    
 DV532_23465 (GbpA)   Pseudomonas sp. Leaf58 AYG47089.1    
 TO66_10640   Pseudomonas sp. MRSN12121 AJO77731.1    
 TO66_17025   Pseudomonas sp. MRSN12121 AJO78890.1    
 TO66_26215   Pseudomonas sp. MRSN12121 AJO80592.1    
 AWU82_10280   Pseudomonas sp. MS586 AMQ83680.1    
 CLM72_18390   Pseudomonas sp. MYb193 AVJ23581.1    
 CLM72_02060   Pseudomonas sp. MYb193 AVJ20583.1    
 C0058_17395   Pseudomonas sp. NC02 AUO23669.1    
 NIBR502773_12885   Pseudomonas sp. NIBRBAC000502773 QDG57369.1    
 NIBR502773_28875   Pseudomonas sp. NIBRBAC000502773 QDG60368.1    
 POS17_2047   Pseudomonas sp. Os17 BAQ73741.1    
 POS17_3900   Pseudomonas sp. Os17 BAQ75594.1    
 POS17_3899   Pseudomonas sp. Os17 BAQ75593.1    
 C3F42_13165 (fragment)   Pseudomonas sp. PONIH3 AUY34113.1    
 C3F42_04220   Pseudomonas sp. PONIH3 AUY32472.1    
 CCX46_18605   Pseudomonas sp. RU47 AZZ77069.1    
 E3Z29_13755   Pseudomonas sp. S150 QBR31537.1    
 EXN22_08475   Pseudomonas sp. SNU WT1 QBF25727.1    
 PST29_3856   Pseudomonas sp. St29 BAQ81745.1    
 PST29_3857   Pseudomonas sp. St29 BAQ81746.1    
 PST29_2139   Pseudomonas sp. St29 BAQ80028.1    
 FH041_13670   Pseudomonas sp. SWI7 QDC05907.1    
 DCC84_18605   Pseudomonas sp. SXM-1 QBQ11617.1    
 THL1_5036   Pseudomonas sp. TCU-HL1 AOE87584.1    
 U771_02460   Pseudomonas sp. TKP AHC33053.1    
 U771_29262   Pseudomonas sp. TKP AHC38315.1    
 PYEL_10980   Pseudomonas sp. URMO17WK12:I11 CRN05341.1    
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