Auxiliary Activity Family 10

Activities in FamilyAA10 (formerly CBM33) proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs); some proteins have been shown to act on chitin, others on cellulose; lytic cellulose monooxygenase (C1-hydroxylating) (EC; lytic cellulose monooxygenase (C4-dehydrogenating)(EC; lytic chitin monooxygenase (EC; lytic xylan monooxygenase / xylan oxidase (glycosidic bond-cleaving) (EC 1.14.99.-)
Mechanism monooxygenase
NoteAA10 (formerly CBM33). The enzymes in this family were originally classified as chitin-binding proteins (CBM33); Vaaje-Kolstad et al. have shown that these proteins are in fact oxidative enzymes [PMID - 20929773]. They are now reclassified in the AA category of CAZy. Because a significant literature is associated with the old name CBM33, we recommend to describe these enzymes as "AA10 (formerly CBM33)".
Statistics GenBank accession (5594); Uniprot accession (382); PDB accession (38); 3D entries (22); cryst (0)
All (5446) Archaea (5) Bacteria (5243) Eukaryota (9) Viruses (185) unclassified (4) Structure (22) Characterized (25)
| 1 | ... | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | ... | 53 |
Protein Name EC#OrganismGenBank UniprotPDB/3D
 M643_07825   Listeria monocytogenes N1-011A AGR14201.1    
 UQ86_12955   Listeria monocytogenes N2306 AJT46157.1    
 BN419_2931   Listeria monocytogenes N53-1 CCQ25141.1    
 CQ02_12525   Listeria monocytogenes NE dc2014 AHN33641.1    
 LMntsn_2414   Listeria monocytogenes NTSN AIZ39703.1    
 M641_00950   Listeria monocytogenes R2-502 AGR24865.1    
 LMR479A_2592   Listeria monocytogenes R479a CDM17807.1    
 N881_2660   Listeria monocytogenes serotype 1/2a str. 01-1280 AHI71248.1    
 A430_2702   Listeria monocytogenes serotype 1/2a str. 08-6569 AHF33326.1    
 A431_2702   Listeria monocytogenes serotype 1/2a str. 08-6997 AHF36317.1    
 A435_2702   Listeria monocytogenes serotype 1/2a str. 10-0815 AHF39308.1    
 A437_2652   Listeria monocytogenes serotype 1/2a str. 10-1047 AHF42249.1    
 A422_2652   Listeria monocytogenes serotype 1/2a str. 88-0478 AHF45190.1    
 A407_2567   Listeria monocytogenes serotype 4b str. 81-0861 AHF30286.1    
 Lm4b_02436   Listeria monocytogenes serotype 4b str. CLIP 80459 CAS06191.1    
 LMOf2365_2440   Listeria monocytogenes serotype 4b str. F2365 AAT05205.1 Q71WW0  
 BN389_24300 (GbpA)   Listeria monocytogenes serotype 4b str. LL195 CCO65004.1    
 LMOSLCC2482_2470   Listeria monocytogenes serotype 7 str. SLCC2482 CBY04991.1    
 ATE46_11650   Listeria monocytogenes SLCC 1090 ALQ25803.1    
 LMOSLCC2372_2529   Listeria monocytogenes SLCC2372 CBY55864.1    
 LMOSLCC2376_2359   Listeria monocytogenes SLCC2376 CBY64391.1    
 LMOSLCC2378_2470   Listeria monocytogenes SLCC2378 CBY74237.1    
 LMOSLCC2479_2528   Listeria monocytogenes SLCC2479 CBY58799.1    
 LMOSLCC2540_2500   Listeria monocytogenes SLCC2540 CBY77141.1    
 LMOSLCC2755_2471   Listeria monocytogenes SLCC2755 CBY50063.1    
 LMOSLCC5850_2469   Listeria monocytogenes SLCC5850 CBY52938.1    
 LMOSLCC7179_2378   Listeria monocytogenes SLCC7179 CBY61584.1    
 LMKH_2524   Listeria monocytogenes VIMHA007 APH80483.1    
 LMVM_2587   Listeria monocytogenes VIMVR081 APH77567.1    
 AX10_06405   Listeria monocytogenes WSLC1001 AHJ04115.1    
 AX24_10260   Listeria monocytogenes WSLC1042 AHJ36503.1    
 UE46_16005   Listeria weihenstephanensis WS 4560 AQY52367.1    
 SAMEA4534872_02546 (Chia1_2)   Listeria welshimeri NCTC11857 SNV29086.1    
 lwe2416   Listeria welshimeri serovar 6b str. SLCC5334 CAK21834.1 A0ALF2  
 FOH38_23810   Lysinibacillus fusiformis 1226 QDQ03214.1    
 D0439_09905   Lysinibacillus fusiformis Cu1-5 QEA01330.1    
 HR49_10600   Lysinibacillus fusiformis RB-21 AJK90028.1    
 A2J09_08490   Lysinibacillus sphaericus 2362 ANA48191.1    
 Bsph_3145   Lysinibacillus sphaericus C3-41 ACA40658.1 B1HQ15  
 Bsph_3198   Lysinibacillus sphaericus C3-41 ACA40707.1 B1HQ64  
 Bsph_p160   Lysinibacillus sphaericus C3-41 ACA42390.1 B1HQ64  
 A1T07_15830   Lysinibacillus sphaericus III(3)7 AMR92925.1    
 A1T07_15830   Lysinibacillus sphaericus III(3)7 AMR92925.1    
 LSP_07490   Lysinibacillus sphaericus KCCM 35418 QAS59196.1    
 AR327_13390   Lysinibacillus sphaericus OT4b.25 AMO35166.1    
 LA76x_0356   Lysobacter antibioticus 76 ALN78518.1    
 GLA29479_4097   Lysobacter antibioticus ATCC 29479 ALN64943.1    
 LC55x_4932   Lysobacter capsici 55 ALN88179.1    
 LC55x_4931   Lysobacter capsici 55 ALN88177.1    
 CNO08_22320   Lysobacter capsici KNU-14 ATE73857.1    
 CNO08_22325   Lysobacter capsici KNU-14 ATE73858.1    
 GLE_4852   Lysobacter enzymogenes C3 ALN60193.1    
 GLE_4851   Lysobacter enzymogenes C3 ALN60192.1    
 LEN_4496 (CpbD)   Lysobacter enzymogenes M497-1 BAV99983.1    
 FE772_23555   Lysobacter enzymogenes YC36 QCW28179.1    
 LG3211_4945   Lysobacter gummosus 3.2.11 ALN93878.1    
 C9I47_0387   Lysobacter maris HZ9B AWV06112.1    
 CR152_01690   Massilia violaceinigra B2 ATQ73360.1    
 MPTP_0965   Melissococcus plutonius ATCC 35311 BAK21424.1    
 DAT1033_0632   Melissococcus plutonius DAT1033 BBP07215.1    
 DAT561_0977   Melissococcus plutonius DAT561 BBC61089.1    
 MPD5_0979   Melissococcus plutonius DAT561 BAL62210.1    
 DAT606_0632   Melissococcus plutonius DAT606 BBD16660.1    
 MEPL_c008580   Melissococcus plutonius S1 AIM24913.1    
 MEBOL_004407   Melittangium boletus DSM 14713 ATB30945.1    
 GTQ55_01725   Microbulbifer hydrolyticus IRE-31 QHQ37836.1    
 GTQ55_15250   Microbulbifer hydrolyticus IRE-31 QHQ40201.1    
 BTJ40_08625   Microbulbifer sp. A4B17 AWF80862.1    
 BTJ40_09285   Microbulbifer sp. A4B17 AWF83414.1    
 BTJ40_19335   Microbulbifer sp. A4B17 AWF82795.1    
 GL2_40920   Microbulbifer sp. GL-2 BBM04018.1    
 GL2_41330   Microbulbifer sp. GL-2 BBM04059.1    
 FIU95_07340 (Gbpa1)   Microbulbifer sp. THAF38 QFT54371.1    
 FIU95_18040 (Gbpa2)   Microbulbifer sp. THAF38 QFT56451.1    
 A3224_13230   Microbulbifer thermotolerans DAU221 AMX03411.1    
 A3224_07945   Microbulbifer thermotolerans DAU221 AMX02527.1    
 SAMN04489812_5219   Microlunatus soli DSM 21800 SDT33013.1    
 Micau_1039   Micromonospora aurantiaca ATCC 27029 ADL44601.1 D9TC53  
 Micau_1630   Micromonospora aurantiaca ATCC 27029 ADL45185.1 D9SZQ3 5OPF[A]
 Micau_3008   Micromonospora aurantiaca ATCC 27029 ADL46539.1 D9TBD4  
 Micau_3953   Micromonospora aurantiaca ATCC 27029 ADL47477.1 D9T1F0  
 Micau_4255   Micromonospora aurantiaca ATCC 27029 ADL47768.1 D9T4V8  
 DVH21_22790   Micromonospora aurantiaca H14(2018) AXH92522.1    
 DVH21_27320   Micromonospora aurantiaca H14(2018) AXH93359.1    
 DVH21_13135   Micromonospora aurantiaca H14(2018) AXH90797.1    
 DVH21_15985   Micromonospora aurantiaca H14(2018) AXH91311.1    
 DVH21_30325   Micromonospora aurantiaca H14(2018) AXH93848.1    
 GA0070611_1762   Micromonospora auratinigra DSM 44815 SBT41835.1    
 GA0070611_2565   Micromonospora auratinigra DSM 44815 SBT44106.1    
 GA0070611_5588   Micromonospora auratinigra DSM 44815 SBT52337.1    
 GA0070611_0003   Micromonospora auratinigra DSM 44815 SBT36889.1    
 GA0070612_5895   Micromonospora chokoriensis DSM 45160 SCF28637.1    
 GA0070612_5891   Micromonospora chokoriensis DSM 45160 SCF28613.1    
 GA0070612_3459   Micromonospora chokoriensis DSM 45160 SCF06262.1    
 GA0070612_3196   Micromonospora chokoriensis DSM 45160 SCF03497.1    
 GA0070607_0964   Micromonospora coriariae DSM 44875 SCE73722.1    
 GA0070607_0969   Micromonospora coriariae DSM 44875 SCE73772.1    
 GA0070607_1570   Micromonospora coriariae DSM 44875 SCE78731.1    
 GA0070607_4482   Micromonospora coriariae DSM 44875 SCF01804.1    
 GA0070614_3056   Micromonospora coxensis DSM 45161 SCG59454.1    

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